Freixa

XavierFreixa Rofastes

Especialista Sènior en Hemodinàmica Cardíaca
Especialitat:
Cardiologia
Especialitats:
  • Cardiologia
Hospitals on treballa:
  • Hospital Universitari General de Catalunya
Informació general
Experiència
  • Formació Especialitzada (MIR)
  • Especialista en Cardiologia a l'Hospital Clínic de Barcelona (2002-2007).
  • Activitats assistencials com a Medico Especialista

- 07/2007 a 12/2008: Fellowship en Cardiologia Intervencionista a l'Hospital Clínic de Barcelona

- 01/2009 a 06/2009: Especialista, Servei de Cardiologia, Hospital Clínic de Barcelona (Cardiologia Intervencionista)

- 07/2009 a 06/2011: Fellowship en Cardiologia Intervencionista al Toronto General Hospital

- 07/2011 a 01/2013: Fellowship en Cardiologia Intervencionista en Cardiopaties Estructurals i Congènites de l'Adult al Montreal Heart Institute.

- 02/2013 fins a l'Actualitat: Especialista Sènior al Servei de Cardiologia Hospital Clínic de Barcelona (Hemodinàmica Cardíaca).

Titulació
  • Llicenciat en Medicina
  • Màster en Gestió Hospitalària i de Serveis Sanitaris (2017-2019). Universitat de Barcelona.
  • Diploma en Estudis Avançats. Universitat de Barcelona
  • Doctorat: Tancament Percutani de l'Orejuela Esquerra: Eficàcia, Seguretat i Noves Perspectives. Universitat de Barcelona. Qualificació: Excel·lent "Cum Laude" amb Menció Internacional.
Tècniques

Coronariografia

Angioplàstia complexa

Reparació mitral amb catèters (Mitraclip, Pascal, Tendyne...)

Reparació tricúspide amb catèters (Triclip, Pascal, TricValve, Navigate…)

Tancament de fuites paravalvulars

Tancament de Foramen Oval Permeable amb diferents dispositius

Tancament d'Orejuela esquerra

TAVI

Reparació de defectes congènits

Hipotèrmia terapèutica

Investigació i docència

Promotor i investigador principal de l'estudi ADALA.

Estudi aleatoritzat de comparació d'apixaban vs. aspirina+clopidogrel després del tancament

percutani d'orella esquerra


Investigador Principal dels estudis següents:

MITRA-CRT. Estudio aleatorizado en pacientes con insuficiencia mitral severa post resincronizacion cardiaca tratados con Mitra-Clip

FIS. Instituto de Salud Carlos III. PI13/01485. Hipotermia terapéutica y riesgo de trombosis: estudio de la actividad plaquetaria y la función endotelial. 2014-2017.

Estudio de cierre de orejuela con Amplatzer Amulet. Amplatzer Amulet Observational Post-Market Study.

Cierre percutáneo de fugas paravalvulares. Registro Nacional y comparativa con cirugía cardiaca.

Cierre FOP/CIA con el nuevo dispositivo Gore Septal Occluder. Registro Nacional.

Cierre percutáneo de la orejuela izquierda. Registro Europeo. Evaluación del cierre con el dispositivo Amplatzer Cardiac Plug versus. Amulet. Evaluación de la severidad de los ictus tras cierre de orejuela izquierda.

Reparación mitral percutánea con el sistema MitraClip. Registro Nacional.

FIS. Instituto de Salud Carlos III. PI080272. Células endoteliales circulantes y células progenitoras endoteliales en la enfermedad cardiovascular aguda. Correlación con la función endotelial y la evolución clínica.

ANDES, PARAVALVULAR LEAK, B-RIGHT, CATALYST, HALTI, ICHROM, DESTINY, LISA, SEQUENT PLEASE


Docència

1. Professor col·laborador a la Universitat Internacional de Catalunya (2014,2015): Responsable de les practiques a la Secció d'Hemodinàmica de l'Hospital General de Catalunya i impartició de seminaris teòric/pràctics.

2. Col·laborador a les pràctiques a la Secció d'Hemodinàmica d'alumnes de Medicina i Biomedicina de la Universitat de Barcelona (2014,2015).

3. Col·laborador a les pràctiques a la Secció d'Hemodinàmica d'alumnes de Biomedicina de la Universitat Pompeu Fabra (2015).

4. Professor a "Màster de Malalt Crític i Emergències" de la Universitat de Barcelona (2015-2016).

5. Professor a "Màster de Competències Avançades de Tractaments Endoluminals i Cardíacs" de la Universitat de Barcelona (2014-2015 i 2015-2016)

Publicacions

1.- Sanchis L, Regueiro A, Cepas-Guillen P, Sitges M, Freixa X. First experience of left atrial appendage occlusion using a 3D mini transoesophageal echocardiographic probe with conscious sedation. EuroIntervention 2023 doi: 10.4244/EIJ-D-22-00921, 2023. ISSN 1774-024X . DOI: 10.4244/EIJ-D-22-00921. IF: 7.728 Q1

2.- I Menduina, X Millan, JA Baz, E Fernandez-Peregrina, Alarcon R, Asmarats L, Cruz-Gonzalez I, Amat-Santos IJ, Melica B, L Nombela-Franco, Pan M, Molina-Ramos Al, Teles R, Freixa X, Li CP, R Estevez-Loureiro, Laura Sanchis. Iberian experience with PASCAL transcatheter edge-to-edge repair for mitral valve regurgitation. Rev Esp Cardiol 2023; 76: 25 - 31. IF: 7.05 Q3

3.- Raposeiras-Roubin S , Adamo M , Freixa X , Arzamendi D et al. A score to assess mortality after percutaneous mitral valve repair. J Am Coll Cardiol 2022;79: 562 - 573. 2022 doi: 10.1016/j.jacc.2021.11.041. IF:24.094 Q1

4.- Solanes N, Bobi J, Arrieta, Jimenez M, Francisco Rafael, Palacios C, Rodriguez, Juan, Roque M, Galan-Arriola C, Ibanez B, Freixa X, Garcia-Alvarez Ana, Sabate M, Rigol M. An open secret in porcine acute myocardial infarction models: The relevance of anaesthetic regimen and breed in ischaemic outcomes. FRONTIERS IN VETERINARY SCIENCE 2022; 9:919454. DOI: 10.3389/fvets.2022.919454 IF: 3.22 Q1

5.- REDUCE LAP-HF II INVESTIGATORS. Atrial shunt device for heart failure with preserved an mildly reduced ejection fraction (REDUCE LAP-HFG II): a randomised, multicentre, blinded, sharm-controlled trial. Lancet 2022; 399: 1130 - 1140. DOI: 10.1016/S0140-6736(22)00016-2 IF: 202.731 Q1 6.- Vij V, Piayda K, Nelles D, Gloekler S, Galea R, Fuerholz M, Meier B, ValgimigliM, O'Hara G, Arzamendi D, Agudelo V, Asmarats, Lluis, Freixa X, Flores-Umanzor E, De Backer O, Sondergaard, Lars, Nombela-Franco L, McInerney A, Korsholm K, Nielsen-Kudsk JE, Afzal S, Zeus T, Operhalski F, Schmidt B, Montalescot G, Guedeney P, Iriart vX, Miton N, Saw J, Gilhofer, Thomas, Fauchier, Laurent, Veliqi, Egzon, Meincke, Felix, Petri, Nils, Nordbeck P, Ognerubov D, Merkulov E, Cruz-Gonzalez, I, Gonzalez-Ferreiro, Rocio, Bhatt, Deepak L., Laricchia A, Mangieri A, Omran H, Schrickel, Jan Wilko, Rodes-Cabau, J, Sievert H, Nickenig G, Sedaghat A. Clinical and echocardiographic risk factors for device-related thrombus after left atrial appendage closure: analysis from the multicenter EUROC-DRT registry. CLINICAL RESEARCH IN CARDIOLOGY 2022;111:1276 - 1285. ISSN 1861-0684 DOI: 10.1007/s00392- 022-02065-4 IF: 5.46 Q1

7.- Sanchis L, Regueiro A, Cepas-Guillen P, Sabate M, Sitges M, Freixa X. Combined left atrial appendage occlusion with other transseptal procedures: should we use the same transseptal puncture?. Rev Esp Cardiol 2022; 75:181 - 182. ISSN 1885-5857 DOI: 10.1016/j.rec.2021.08.005 IF: 7.05 Q3

8.- Haberman D, Estevez-Loureiro R, Benito-Gonzalez T, Denti P, Arzamendi D, Adamo M, Freixa X, Nombela-Franco L, Villablanca P, Krivoshei L, Fam N, Spargias K, Czarnecki A, Pascual I, Praz F, Sudarsky D, Kerner A, Ninios V, Gennari M, Beeri R, Perl L, Wasserstrum Y, Danenberg H, Poles L, George J, Caneiro-Queija B, Scianna S, Moaraf I, Schiavi D, Scardino C, Corpataux Noe, Echarte-Morales J, Chrissoheris M, Fernandez-Peregrina E, Di Pasquale M, Regueiro A, Vergara-Uzcategui C, Iniguez-Romo A, Fernandez-Vazquez F, Dvir D, Maisano F, Taramasso M, Shuvy M. Conservative, surgical, and percutaneous treatment for mitral regurgitation shortly after acute myocardial infarction. EUROPEAN HEART JOURNAL 2022;43; 641 - 650. ISSN 0195-668X DOI: 10.1093/eurheartj/ehab496 IF: 29.983 Q1

9.- Gonzalez-de Pa L, Kostov B, Freixa X et al. Cost-accuracy andpatient experience assessment of blood pressure monitoring methods to diagnose hypertension: A comparative effectiveness study. FRONTIERS IN MEDICINE 2022; 9: 827821. DOI: 10.3389/fmed.2022.827821 IF:5.058 Q1

10.- Mill J, Montoliu H, Moustafa Abdel H., Olivares Andy L, Albors C, Aguado Ainhoa M, Medina E, Ceresa M, Freixa X et al. Expert evaluation of advanced visual computing solutions and 3D printing for the planning of the left atrial appendage occlude interventions. INTERNATIONAL JOURNAL OF BIOPRINTING 2022;9:640. ISSN 2424-7723DOI:

10.18063/ijb.v9i1.640 IF:6,39 Q1

11.-Mesnier J, Cruz-Gonzalez I, Arzamendi D, Freixa X et al. Early Discontinuation of Antithrombotic Treatment Following Left Atrial Appendage Closure. AMERICAN JOURNAL OF CARDIOLOGY 2022;171:91 - 98. ISSN 0002-9149 DOI: 10.1016/j.amjcard.2022.01.055 IF:2,55 Q1

12.- Freixa X, Tolosana JM, Cepas-Guillen Pedro L, Hernandez-Enriquez M, Sanchis L, Flores- Umanzor E, Farrero, M et al. Edge-to-Edge Transcatheter Mitral Valve Repair Versus Optimal Medical Treatment in Nonresponders to Cardiac Resynchronization Therapy: The MITRA-CRT Trial. CIRCULATION-HEART FAILURE 2022; 15: e009501. ISSN 1941-3289 DOI: 10.1161/CIRCHEARTFAILURE.121.009501 IF:8,79 Q1

13.- Flores-Umanzor E, Cepas-Guillen P, Freixa X. Erythromelalgia improvement after percutaneous tricuspid regurgitation repairment in a patient with polycythemia vera. Medicina clinica 2022; 159:606. ISSN 0025-7753 DOI: 10.1016/j.medcli.2022.08.004 IF:3,2

Q3

14.- Flores-Umanzor E, Cepas-Guillen P, Regueiro A, Sanchis L, Ibanez Cristina, Sitges M, Rodes-Cabau J, Freixa X. Half-Dose DOAC After Watchman Implantation. JACC CARDIOVASCULAR INTERVENTIONS 2022;15:342. ISSN 1936-8798 DOI: 10.1016/j.jcin.2021.11.015 IF:11,195 Q1

15.- Li CP, Estevez-Loureiro R, Freixa X et al. Iberian experience with PASCAL transcatheter edge-to-edge repair for mitral valve regurgitation. Rev Esp Cardiol 2022; 76:25 - 31. DOI: 10.1016/j.rec.2022.05.003 IF: 7,05 Q3

16. Flores-Umanzor E, Cepas-Guillen P, Alvarez-Contreras L, Caldentey G, Castrillo-Golvano L, Fernandez-Valledor A, Salazar-Rodriguez A, Arevalos V, Gabani R, Regueiro A, Brugaletta S, Roque, M, Freixa X, Martin-Yuste V, Sabate Manel. Impact of Chronic Kidney Disease in Chronic Total Occlusion Management and Clinical Outcomes. CARDIOVASCULAR REVASCULARIZATION MEDICINE 2022; 38:75 - 80. ISSN 1553-8389 DOI: 10.1016/j.carrev.2021.07.018 IF:1,168 Q3

17.-Mesnier J, Cruz-Gonzalez I, Arzamendi D, Freixa X et al. Incidence and Predictors of Early Death in Patients Undergoing Percutaneous Left Atrial Appendage Closure. JACC-CLINICAL ELECTROPHYSIOLOGY 2022;8:1093 - 1102. ISSN 2405-500X DOI: 10.1016/j.jacep.2022.06.012 IF:6,375 Q1

18.- Luis Cepas-Guillen P, Lopez-Minguez, J, Nunez Garcia, J, Nombela-Franco, Luis, Benito- Gonzalez, T, Cruz-Gonzalez I, Freixa X. Left Atrial Appendage Occlusion in Hereditary Haemorrhagic Telangiectasia Patients (Rendu Osler Syndrome) With Non-Valvular Atrial Fibrillation: Prevention of Cardioembolic Events While Avoiding the Long-Term Risks of Oral Anticoagulation. CARDIOVASCULAR REVASCULARIZATION MEDICINE 2022;43:140 - 142. ISSN 1553-8389 DOI: 10.1016/j.carrev.2022.04.005 IF:1,168 Q3

19.- Cepas-Guillen PL, Schmidt B, Berti S, Fischer S, Magnusson K, Skurk C, Zeus T, Freixa X. Left Atrial Appendage Occlusion in Nonagenarians.The Journal of invasive cardiology 2022; 34:E296 - E298. 2022. ISSN 1042-3931 PMID: 35157606 IF:2,022 Q2

20.- Marroquin L, Tirado-Conte G, Praco R, Streb W, Gutierrez H, Boccuzzi G, Arzamendi- Aizpurua D, Cruz-Gonzalez I, Ruiz-Nodar J, Kim J, Freixa X et al. Management and outcomes of patients with left atrial appendage thrombus prior to percutaneous closure. HEART 2022;108:pp. 1098 -1106. ISSN 1355-6037. DOI: 10.1136/heartjnl-2021-319811 IF:5,994 Q1

21.- Tirado-Conte G, Gomez-Alvarez Z, Gheorghe L, Asmarats L, Jimenez-Quevedo, P, Regueiro A, Garcia Gamez A, McInerney A, Li, Chi-Hion Pedro, Pozo E, Freixa X, Nombela L. Neo-Commissural Alignment and Coronary Artery Overlap Following Portico Aortic Valve Implantation. JACC-CARDIOVASCULAR INTERVENTIONS 2022;15:1590 - 1592. ISSN 1936- 8798DOI: 10.1016/j.jcin.2022.06.010 IF:11,075 Q1

22.-Cepas-Guillen P, Echarte-Morales J, Caldentey G, Martinez Gomez E, Flores-Umanzor E, Borrego-Rodriguez, J, Llagostera M, Viana Tejedor A, Vidal P, Benito-Gonzalez T, Quiroga X, Fernandez Ortiz, A, Freixa X, Perez de Prado A, Noriega Sanz F, Fernandez-Vazquez F, Sabate M. Outcomes of Nonagenarians With Acute Coronary Syndrome. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION 2022; 23:81 - 86 e4. ISSN 1525-8610 DOI: 10.1016/j.jamda.2021.04.027 IF:4,669 Q1

23.- Freixa X, Gabani R, Cepas-Guillen P et al. Paravalvular Leakages after Surgical Aortic- Valve Replacement and after Transcatheter Aortic-Valve Implantation: Strategies to Increase the Success Rate of Percutaneous Closure. JOURNAL OF CLINICAL MEDICINE 2022; 11: 2989. DOI: 10.3390/jcm11112989 IF:4,81 Q1

24.- Sanchis L, Vidal B, Freixa X. Paravalvular mitral shunt percutaneously closed with a plug. Rev Esp Cardiol 2022; 75:525. ISSN 1885-5857 IF: 7,05 DOI: 10.1016/j.rec.2021.11.01 IF:6,975 Q

25.-Antunez-Muinos P, Vicente-Palacios V, Perez-Sanchez P, Sampedro-Gomez J, Sanchez- Puente, A, Dorado-DiazP, Nombela-Franco L, Salinas P, Gutierrez-Garcia H, Amat-Santos I, Peral V, Morcuende A, Asmarats L, Freixa X. Predictive Power for Thrombus Detection after Atrial Appendage Closure: Machine Learning vs. Classical Methods. JOURNAL OF PERSONALIZED MEDICINE 2022; 12:1413. DOI: 10.3390/jpm12091413 IF:4,453 Q2

26.-Freixa X, Estevez-Loureiro R, Pascual I, Carrasco-Chinchilla F, Sanchis L et al. Procedural and clinical outcomes after repeat edge-to-edge transcatheter mitral valve repair. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2022; 99:1619- 1625. ISSN 1522- 1946. DOI: 10.1002/ccd.30053 IF:2,585 Q1

27.-Caneiro-Queija B, Raposeiras-Roubin S, Adamo M, Freixa X, Arzamendi D et al. Prognostic Impact of Nutritional Status After Transcatheter Edge-to-Edge Mitral Valve Repair: The MIVNUT Registry. JOURNAL OF THE AMERICAN HEART ASSOCIATION 2022; 11:e023121. 2022. DOI: 10.1161/JAHA.121.023121 IF:5,501 Q1

28.-Benini Tapias J, Flores-Umanzor E, Cepas-Guillen Pedro L, Regueiro A, Sanchis L, Jesus Broseta, Jose, Cases A, Freixa X. Prognostic impact of the presence of chronic kidney disease on percutaneous left trial appendage closure for atrial fibrillation: A single center experience. NEFROLOGIA 2022; 42, pp. 290 - 300. ISSN 0211-6995 DOI: 10.1016/j.nefro.2021.02.008 IF:2,033 Q3

29.-Freixa X, Jurado-Roman A, Cid B, Cruz-Gonzalez I. Spanish cardiac catheterization and coronary intervention registry. 31st official report of the Interventional Cardiology Association of the Spanish Society of Cardiology (1990-2021). Rev Esp Cardiol 2022; 75: 1040- 1049. ISSN 03008932 / DOI: 10.1016/j.recesp.2022.08.008 IF: 7,05 Q3 30.-Flores-Umanzor E, Cepas-Guillen P.L, Sanchis L, Regueiro A, Diaz-Ricart M, Freixa X. Spontaneous echo-contrast and prothrombotic status in patients undergoing left atrial appendage occlusion. Rev Esp Cardiol 2022; 75: 966 - 969. ISSN 03008932. DOI:

10.1016/j.recesp.2022.03.022 IF: 7,05 Q3 31.-Barrero A., Carrasco-Chinchilla F., Benito-Gonzalez T., Pascual I., Arzamendi D., Estevez- Loureiro R, Nombela-Franco L, Pan M, Freixa X et al. Temporal trend and potential impact of angiotensin receptor neprilysin inhibitors on transcatheter edge-to-edge mitral valve repair. Rev Esp Cardiol 2022;75:1001 - 1010. ISSN 03008932 DOI: 10.1016/j.recesp.2022.02.001 IF: 7,05 Q3

32.-Freixa X, Arzamendi D, del Trigo M, Cepas-Guillen P, Li P et al. The TriClip system for edge-to-edge transcatheter tricuspid valve repair. A Spanish multicenter study. Rev Esp Cardiol 2022;75:797 - 804. ISSN 1885-5857 DOI: 10.1016/j.rec.2022.01.007 IF: 7,05 Q3

33.-Alper A, Guedeny P, Horlick E, Nombela-Franco L, Freixa X et al.Transcatheter Closure of Patent Foramen Ovale in Older Patients With Cryptogenic Thromboembolic Events. CIRCULATION-CARDIOVASCULAR INTERVENTIONS 2022; 15: e011652. ISSN 1941-7640 22. DOI: 10.1161/CIRCINTERVENTIONS.121.011652 IF: 6,546 Q1

34.-Fernandez-Peregrina E, Pascual I, Freixa X et al. Transcatheter edge-to-edge mitral valve repair in patients with mitral annulus calcification. EUROINTERVENTION 2022; 17:1300 - 1309. ISSN 1774-024X DOI: 10.4244/EIJ-D-21-00205. IF: 6,534 Q1

35.-Cepas-Guillen P, Pascual I, Garcia E, Jimenez-Quevedo P, Jurado-Roman A, Benito- Gonzalez T, Estevez-Loureiro R, Li P, Arzamendi D, Melica B, Infante de Oliveira E, Martin Lorenzo P, Fernandez-Vazquez F, Galeote G, Nombela-Franco L, Unzue L, Avanzas P, Sabate M, Freixa X. Transcatheter mitral valve repair in nonagenarians. JOURNAL OF GERIATRIC CARDIOLOGY 2022; 19:90 - 94. ISSN 1671-5411 DOI: 10.11909/j.issn.1671-5411.2022.01.007 IF: 2,06 Q2 36.-Flores-Umanzor E, Cepas-Guillen P, Regueiro A, Sanchis L, Unigarro F, Brugaletta S, Sitges M, Sabate M, Freixa X. Treatment of Device-Related Thrombosis After Left Atrial Appendage Occlusion: Initial Experience With Low-Dose Apixaban. Cardiovascular Revascularization Medicine 2022.;40: 201 - 203. DOI: 10.1016/j.carrev.2021.11.007 IF: 1,23 Q3

37.- Freixa X, Cepas-Guillen P, Korsholm K, Kramer A, Regueiro A, Flores-Umanzor E, Sanchis L, Arenas-Loriente A, Jensen J, Nielsen-Kudsk JE. Usefulness of a novel sizing chart for left atrial appendage occlusion with the Amplatzer Amulet. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2022;100:801 - 809. ISSN 1522-1946 DOI: 10.1002/ccd.30406 IF:2,585 Q1

38.- Cepas Guillen PL , Echarte Morales J, Flores Umanzor E, Fernandez Valledor A, Caldentey A, Viana Tejedor A, Martinez Gomez E, Tundidor Sanz E, Borrego Rodriguez J, Vidal P, Llagostera M, Quiroga X, Freixa X et al. Sex gender disparaties in nonagenarians with acute coronary syndrome. Clin Cardiol 2021; 44:371 - 378. 19/01/2021. DOI: 10.1002/clc.23545 IF:2,86 Q1

39.- Flores-Umanzor E, Pujol-Lopez M, Cepas P, Caldentey G, Freixa X et al. A rare cause of non-infectious sialadenitis: Iodide-induced sialadenitis associated with coronary angiography. REVISTA PORTUGUESA DE CARDIOLOGIA 2021; 40:395 - 397. ISSN 0870-2551 /DOI: 10.1016/j.repc.2021.03.002 IF:1,374 Q3

40.- Arevalos V, Rodriguez-Arias JJ, Brugaletta S, Micari A, Costa F, Freixa X et al. Alcohol Septal Ablation: An Option on the Rise in Hypertrophic Obstructive Cardiomyopathy. JOURNAL OF CLINICAL MEDICINE. 10, 2021. DOI: 10.3390/jcm10112276 IF:4,81 Q1

41.- Sanchis L, Cepas Pedro L, Perez Fuente P, Carraminana A, Flores E, Farrero M, Regueiro A, Sabate M, Sitges M, Freixa X. Amplatzer Vascular Plug III and Interclip Mitral Regurgitation A Good Alternative When Another Clip Doesn't Fit. JACC-CARDIOVASCULAR INTERVENTIONS 2021; 14: e9 - e10. ISSN 1936-8798 DOI: 10.1016/j.jcin.2020.10.021 IF:11,075 Q1

42.- Sanchis L, Farrero M, Martinez D, Castel A, Sandoval E, Alcocer J, Regueiro A, Flores-Umanzor E, Cepas-Guillen P, Sabate M Sitges M, Freixa X. Anatomical Fusion of MitraClip Device With Native Mitral Apparatus Insights From an Explanted Human Heart. JACCCARDIOVASCULAR INTERVENTIONS 2021;14:1257 - 1258. ISSN 1936-8798 DOI: 10.1016/j.jcin.2021.03.023 IF:11,075 Q1

43.- Trasca L, Sanchis L, Regueiro A, Freixa X, Vinereanu D, Sitges M. Changes in mitral valve geometry after percutaneous valve repair with the MitraClip (R) System. INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 2021; 37:1577 - 1585. ISSN 1569-5794 DOI: 10.1007/s10554-020-02137-4 IF:2.3 Q2

44.- Alvarez-Contreras L, Flores-Umanzor E, Cepas-Guillen P, Ferreira-Gonzalez I, Freixa X, Regueir A, Brugaletta S, Sabate M, Martin-Yuste V. Clinical Impact of Medical Therapy Versus Revascularization in Patients With Chronic Coronary Total Occlusions. JOURNAL OF INVASIVE CARDIOLOGY 2021; 33:E2 - E8. ISSN 1042-3931 IF:1.06 Q2

45.- Benito-Gonzalez T, Carrasco-Chinchilla F, Estevez-Loureiro R, Pascual I, Arzamendi D, Garrote-Coloma C, Nombela-Franc L, Pan M, Serrador Ana, Freixa X et al. Clinical and echocardiographic outcomes of transcatheter mitral valve repair in atrial functional mitral regurgitation. INTERNATIONAL JOURNAL OF CARDIOLOGY 2021; 345: 2021. ISSN 0167-5273 /DOI: 10.1016/j.ijcard.2021.09.056 IF:4.039 Q1

46.-Freixa X, Schmidt B, Mazzone P et al. Comparative data on left atrial appendage occlusion efficacy and clinical outcomes by age group in the Amplatzer (TM) Amulet (TM) Occluder Observational Study. EUROPACE 2021; 23:238 - 246. ISSN 1099-5129 DOI: 10.1093/europace/euaa262 IF:5,486 Q1

47.-Flores-Umanzor, E, Cepas-Guillen, P, Sanchis, L, Regueiro A, Navarro R, Brugaletta S, Vidal B, Sitges M, Sabate M, Freixa X. Device related thrombosis after left atrial appendage occlusion: does thrombus location always predicts its origin?. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY 2021; 60:347 - 348. ISSN 1383-875X DOI: 10.1007/s10840- 020-00819-6. IF: 1.759 Q2

48.- Sedaghat A, Vij V, Al-Kassou B, Gloekler S, Gale R, Furholz M, Meier B, Valgimigli M, O'Hara G, Arzamendi D, Agudelo V, Asmarats L, Freixa X et al. Device-Related Thrombus After Left Atrial Appendage Closure Data on Thrombus Characteristics, Treatment Strategies, and Clinical Outcomes From the EUROC-DRT-Registry. CIRCULATION-CARDIOVASCULAR INTERVENTIONS 2021; 14:e010195. ISSN 1941-7640 DOI: 10.1161/CIRCINTERVENTIONS.120.010195 IF: 6.546 Q1

49.-Cruz-Gonzalez I, Trejo-Velasco B, Freixa X et al. Double LAmbre technique for percutaneous occlusion of very large left atrial appendages: a case series.EuroIntervention 2022; 18: 58 - 62. ISSN 1774-024X DOI: 10.4244/EIJ-D-21-00512 IF: 7.728 Q1

50.-ENVISAGEM TAVI AF Investigators. Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR. NEW ENGLAND JOURNAL OF MEDICINE 2021; 385 :2150 - 2160. ISSN 0028-4793 / DOI: 10.1056/NEJMoa2111016 IF:70.670 Q1

51.-Faroux L, Cruz-Gonzalez I, Arzamendi D, Freixa X et al. Effect of Glomerular Filtration Rates on Outcomes Following Percutaneous Left Atrial Appendage Closure.The American journal of cardiology 2021; 145: 77 - 84. ISSN 0002-9149 DOI: 10.1016/j.amjcard.2020.12.081 IF:2.55 Q1

52.-Aminian, Adel, De Backer, Ole, Nielsen-Kudsk, Jens Erik, Mazzone, Patrizio, Berti, Sergio, Fischer, Sven, Lund, Juha, Montorfano, Matteo, Lam, Simon Cheung Chi, Freixa X, Gage, Ryan, Diener, Hans-Christoph, Schmidt, Boris. Incidence and clinical impact of major bleeding following left atrial appendage occlusion: insights from the Amplatzer Amulet Observational Post-Market Study. EUROINTERVENTION 2021; 17:774 - 782. ISSN 1774-024X DOI: 10.4244/EIJ-D-20-01309. IF: 7.728 Q1

53.-Faroux L, Cruz-Gonzalez I, Arzamendi D, Freixa X et al. Incidence, predictors, and clinical impact of bleeding recurrence in patients with prior gastrointestinal bleeding undergoing LAAC. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 2021; 44:1216 - 1223. ISSN 0147- 8389 DOI: 10.1111/pace.14293 IF:1.37 Q2

54.-Cepas-Guillen P, de la Fuente Mancera JC, Guzman Bofarull J, Farrero M, Regueiro A, Brugaletta S, Ibanez C, Sanchis L, Sitges M, Sabate M, Freixa X. Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program. JOURNAL OF CLINICAL MEDICINE 2021; 10:4252 . DOI: 10.3390/jcm10184252 IF:4.964 Q1 55.-PL Cepas Guillen, Juan C de la Fuente, J Guzman, M Farrero, A Regueiro, S Brugaletta, C Ibanez, L Sanchis,M Sitges, M Sabate, Freixa X. Initial results after the implementation of an Edge-to-Edge Transcatheter tricuspid valve repair program. J Clin Med. 2021. DOI: 10.3390/jcm10184252 IF:5.994 Q1

56.-Freixa X, Tzikas A, Aminian A, Flores-Umanzor E et al. Left atrial appendage occlusion in chicken-wing anatomies: Imaging assessment, procedural, and clinical outcomes of the "sandwich technique". CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2021; DOI: 10.1002/ccd.29546 IF:2.585 Q1

57.-Cepas PL, Flores E, Regueiro A, Brugaletta S, Ibanez C, Sanchis L, Sitges M, Sabate M, Rodes J, Freixa X. Low dose of direct oral anticoagulants after Left Atrial Appendage Occlusion. J Cardiovasc Dev Dis 2021; 8 – 11:142. 2021. DOI: 10.3390/jcdd8110142 IF:3.948 Q1

58.-Spione F, Brugaletta S, Freixa X, Arevalos V, Sabate M. May LAAO Learning Curve Explain the Relationship Between Procedural Volume and Complications Rate?. JACCCARDIOVASCULAR INTERVENTIONS 2021; 14:1263 - 1264. ISSN 1936-8798 DOI: 10.1016/j.jcin.2021.04.002 IF:11.075 Q1

59.-Lee, Oh-Hyun, Kim, Young Dae, Kim, Jung-Sun, Son, Nak-Hoon, Pak, Hui-Nam, Joung, Boyoung, Yu, Cheol-Woong, Lee, Hyun-Jong, Kang, Woong-Chol, Shin, Eun-Seok, Choi, Rakkyeong, Lim, Do-Sun, Jung,Yo Han, Choi, Hye-Yeon, Lee, Kyung-Yul, Cho, Bang-Hoon, Han, Sang Won, Park, Joong Hyun, Cho, Han-Jin, Park, Hyung Jong, Nam, Hyo Suk, Heo, Ji Hoe, So, Chak-yu, Cheung, Gary Shing-Him, Lam, Yat-yin, Freixa X et al. Percutaneous Left Atrial Appendage Occlusion Yields Favorable Neurological Outcomes in Patients with Non-Valvular Atrial Fibrillation. KOREAN CIRCULATION JOURNAL 2021;51: 626 - 638. ISSN 1738-5520 DOI: 10.4070/kcj.2020.0527 IF:3.101 Q2

60.-Freixa X, Estevez-Loureiro R, Carrasco-Chinchilla et al. Percutaneous Mitral Valve Repair: Outcome Improvement with Operator Experience and a Second-Generation Device. JOURNAL OF CLINICAL MEDICINE 2021; 10:734. DOI: 10.3390/jcm10040734 IF:4.964 Q1

61.-Simard, Trevor, Jung, Richard G., Lehenbauer, Kyle, Piayda, Kerstin, Pracon, Radoslaw, Jackson, Gregory G., Flores-Umanzor, Eduardo, Faroux, Laurent, Korsholm, Kasper, Chun, Julian K. R., Chen, Shaojie, Maarse, Moniek, Montrella, Kristi, Chaker, Zakeih, Spoon, Jocelyn N., Pastormerlo, Luigi E., Meincke, Felix, Sawant, Abhishek C., Moldovan, Carmen M., Qintar, Mohammed, Aktas, Mehmet K., Branca, Luca, Radinovic, Andrea, Ram, Pradhum, El-Zein, Rayan S., Flautt, Thomas, Ding, Wern Yew, Sayegh, Bassel, Benito-Gonzalez, Tomas, Lee, Oh-Hyun, Badejoko, Solomon O., Paitazoglou, Christina, Karim, Nabeela, Zaghloul, Ahmed M., Agrawal, Himanshu, Kaplan, Rachel M., Alli, Oluseun, Ahmed, Aamir, Suradi, Hussam S., Knight, Bradley P., Alla, Venkata M., Panaich, Sidakpal S Wong, Martin W, Chothia, Rashaad, Kim, Jung-Sun, Perez de Prado, Armando, Bazaz, Raveen, Gupta, Dhiraj, Valderrabano, Miguel, Sanchez, Carlos E, El Chami, Mikhael F., Mazzone, Patrizio, Adamo, Marianna, Ling, Fred, Wang, Dee Dee, O'Neill, William, Wojakowski, Wojtek, Pershad, Ashish, Berti, Sergio, Spoon, Daniel, Kawsara, Akram, Jabbour, George, Boersma, Lucas V. A., Schmidt, Boris, Nielsen-Kudsk, Jens Erik, Rodes-Cabau, Josep, Freixa X et al. Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2021; 78:297 - 313. ISSN 0735-1097 DOI: 10.1016/j.jacc.2021.04.098 IF:24.094 Q1

62.-Trejo-Velasco, Blanca, Estevez-Loureiro, Rodrigo, Carrasco-Chinchilla, Fernando, Fernandez-Vazquez, Felipe, Arzamendi, Dabit, Pan, Manuel, Pascual, Isaac, Nombela-Franco,Luis, Amat-Santos, Ignacio J., Freixa X et al. Prognostic Role of TAPSE to PASP Ratio in Patients Undergoing MitraClip Procedure. JOURNAL OF CLINICAL MEDICINE 2021; 10: 1006. DOI: 10.3390/jcm10051006 IF:4.964 Q1

63.-Benini Tapias J, Flores-Umanzor E, Cepas-Guillen PL, Regueiro A, Sanchis L, Broseta JJ, Cases A, Freixa X. Prognostic impact of the presence of chronic kidney disease on percutaneous left trial appendage closure for atrial fibrillation: A single center experience. Nefrologia 2021; S0211-6995:00130-2 / DOI: 10.1016/j.nefro.2021.02.008 IF: IF:3.084 Q3

64.-Freixa X, Cepas-Guillen, Pedro, Flores-Umanzor, Eduardo et al. Pulmonary ridge coverage and device-relatedthrombosis after left atrial appendage occlusion. EUROINTERVENTION 2021; 16: e1288 - e1294. ISSN 1774-024X / DOI: 10.4244/EIJ-D-20-00886. IF: 7.728 Q1

65.-Haberman D, Estevez-Loureiro R, Benito-Gonzalez T, Denti P, Arzamendi D, Adamo M, Freixa X et al. Safety and Feasibility of MitraClip Implantation in Patients with Acute Mitral Regurgitation after Recent Myocardial Infarction and Severe Left Ventricle Dysfunction. JOURNAL OF CLINICAL MEDICINE 2021; 10:1819. DOI: 10.3390/jcm10091819 IF: IF: 4.964 Q1

66.-Faroux L, Cruz-Gonzalez I, Arzamendi D, Freixa X et al. Short-term direct oral anticoagulation or dual antiplatelet therapy following left atrial appendage closure in patients with relative contraindications to chronic anticoagulation therapy. INTERNATIONAL JOURNAL OF CARDIOLOGY 2021; 333: 77 - 82. ISSN 0167-5273 / DOI: 10.1016/j.ijcard.2021.02.054 IF: IF:4.039 Q1

67.-Flores-Umanzor, Eduardo J., Cepas-Guillen, Pedro L., Vazquez, Sara, Fernandez-Valledor, Andrea, Ivey-Miranda, Juan, Izquierdo, Marc, Caldentey, Guillem, Jimenez-Britez, Gustavo, Regueiro, Ander, Freixa X et al. Survival benefit of revascularization versus optimal medical therapy alone for chronic total occlusion management in patients with diabetes.CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2021; 97:376 - 383. ISSN 1522-1946 / DOI: 10.1002/ccd.28815 IF:2.585 Q1

68.-Mesnier J, Cruz-Gonzalez I, Peral V, Nombela-Franco L, Freixa X, Laffond A, Mas-Llado C, McInerney A, Regueiro A, O'Hara G, Rodes-Cabau J. Ten-Year Outcomes Following Percutaneous Left Atrial Appendage Closure in Patients With Atrial Fibrillation and Absolute or Relative Contraindications to Chronic Anticoagulation. CIRCULATION-CARDIOVASCULAR INTERVENTIONS 2021;14: e010821. ISSN 1941-7640DOI: 10.1161/CIRCINTERVENTIONS.121.010821 IF:3.084 Q1

69.-Estevez-Loureiro R, Shuvy M, Taramasso M, Benito-Gonzalez T, Denti P, Arzamendi D, Adamo M, Freixa X et al. Use of MitraClip for mitral valve repair in patients with acute mitral regurgitation following acute myocardial infarction: Effect of cardiogenic shock on outcomes (IREMMI Registry). CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2021; 97: 1259 - 1267. ISSN 1522-1946 DOI: 10.1002/ccd.29552 IF:2.585 Q1

70.-Armijo G, Estevez-Loureiro R, Carrasco-Chinchilla F, Arzamendi D, Pan M, Fernandez- Vazquez F, Alonso-Briales JH, Freixa X et al. Acute kidney injury after percutaneous edge-to-edge mitral repair. J Am Coll Cardiol 2020; 76:2463 - 2473. DOI: 10.1016/j.jacc.2020.09.582 IF:24.094 Q1

71.-Gomez-Lara J, Ortega-Paz L, Brugaletta S, Cuesta J, Romani S, Serra A, Salinas P, Garcia del Blanco B, Goicolea J, Hernandez-Antolin R, Antuna P, Romaguera R, Regueiro A, Rivero, F, Cequier A, Alfonso F, Gomez-Hospital J, Sabate M, Freixa X, Masotti M, Ferreiro JL, Roura G, Bustamante T, Jimenez M, Otaegui I, Bordes P, Iniguez A. Bioresorbable scaffolds versus permanent sirolimus-eluting stents in patients with ST-segment elevation myocardial infarction: vascular healing outcomes from the MAGSTEMI trial. EUROINTERVENTION 2020; 16:e913 - e921. ISSN 1774-024X DOI: 10.4244/EIJ-D-20-00198. IF: 7.728 Q1

72.-Rodriguez-Arias Juan J, Ortega-Paz L, Brugaletta S, Freixa X et al. Comparison of clinical outcomes in STEMI patients treated with primary PCI according to day-time of medical attention and its relationship with circadian pattern. INTERNATIONAL JOURNAL OF CARDIOLOGY 2020; 305:35 - 41. ISSN 0167-5273 DOI: 10.1016/j.ijcard.2020.01.041 IF: IF:4.039 Q1

73.-Sanchis L, Quintana E, Navarro R, Farrero M, Sandoval E, Fernandez-Cisneros A, Regueiro A, Sabate M Sitges, M, Freixa X. Delayed Mitral Leaflet Perforation in a Tethered Valve After MitraClip XTR Implantation. JACC-CARDIOVASCULAR INTERVENTIONS 2020; 13:2438 - 2439. ISSN 1936-8798 / DOI: 10.1016/j.jcin.2020.06.054 IF:11.075 Q1

74.-Mill J, Olivares Andy L, Arzamendi D, Agudelo V, Regueiro A, Camara O, Freixa X. Impact of Flow Dynamics on Device-Related Thrombosis After Left Atrial Appendage Occlusion. CANADIAN JOURNAL OF CARDIOLOGY 2020; 36:968.e13 - 968.e14. ISSN 0828-282X DOI: 10.1016/j.cjca.2019.12.036 IF: IF:6.614 Q1

75.-Bobi J, Garabito M, Solanes N, Cidad P, Ramos-Perez V, Ponce A, Rigol M, Freixa X et al. Kv1.3 blockade inhibits proliferation of vascular smooth muscle cells in vitro and intimal hyperplasia in vivo. TRANSLATIONAL RESEARCH 2020;224:40 - 54. ISSN 1931-5244 DOI: 10.1016/j.trsl.2020.06.002 IF: IF:10.171 Q1

76.-Cruz-Gonzalez I, Gonzalez-Ferreiro R, Freixa X et al. Left atrial appendage occlusion for stroke despite oral anticoagulation (resistant stroke). Results from the Amplatzer Cardiac Plug registry. Rev Esp Cardiol 2020;73:28-34. ISSN 1885-5857 / DOI: 10.1016/j.recesp.2019.02.018 IF: 7.05 Q3

77.- Freixa X, Aminian A, De Backer O, Berti S, JE Nielsen-Kudsk. Left atrial appendage occlusion in COVID-19 times. Eur Heart J Supplement 2020; 22 – Suppl:47 - P52. DOI: 10.1093/eurheartj/suaa173 IF: 1.624 Q3

78.-Freixa X, Aminian A, Tzikas A, Saw J, Nielsen JE, Ghanem A, Schmidt B. Left atrial appendage occlusion with the Amplatzer Amulet, update on device sizing. J Interv Card Electrophysiol 2020; 59 – 1:71 - 78. DOI: 10.1007/s10840-019-00699-5 IF:1.759 Q2

79.-Lopez-Minguez JR, Nogales-Asensio M, De Oliveira J, Infante, Santos E, Ruiz-Salmeron R, Arzamendi-Aizpurua D, Costa M, Gutierrez-Garcia H, Fernandez-Diaa J, Freixa X et al. Major Bleeding Predictors in Patients with Left Atrial Appendage Closure: The Iberian Registry II. JOURNAL OF CLINICAL MEDICINE 2020; 9:2295. DOI: 10.3390/jcm9072295 IF: IF:4.81 Q1

80.-Sanchis L, Jorda P, Pereda D, Garcia Alvarez A, Perdomo Juan M, Regueiro A, Sabate M, Sitges M, Freixa X. MitraClip Implantation for Hemolytic Anemia Treatment After Surgical MitralmValve Repair. JACC-CARDIOVASCULAR INTERVENTIONS 2020; 13:e85 - e86. ISSN 1936-8798. DOI: 10.1016/j.jcin.2020.01.198 IF:11.075 Q1

81.- Bobi J, Solanes N, Dantas AP, Ishida K, Regueiro A, Castillo N, Sabate M, Rigol M, Freixa X. Moderate hypothermia modifies coronary hemodynamics and endothelium-dependent vasodilation in a porcine model of temperature management. J Am Heart Assoc. 2020; 9 – 3: e014035. DOI: 10.1161/JAHA.119.014035 IF: 6.106 Q1

82.-Cepas P, Borrego J, Flores E, Echarte-Morales J, Fernandez A, Menendez P, Vazquez S, Alonso N, Ortiz JT, Regueiro A, Iglesias I, Andrea R, Masotti M, Perez de Prado A, Brugaletta S, Bayon J, Freixa X, Fernandez F, Sabate M. Outcomes of nonagenarians with ST Elevation Myocardial Infarction. Am J Cardiol 2020; 125 – 1:11 - 18. DOI: 10.1016/j.amjcard.2019.09.046 IF: 3.133 Q1

83.- Xipell, Marc, Flores-Umanzor, Eduardo, Ojeda, Raquel, Arias, Marta, Cepas-Guillen, Pedro L., Regueiro, Ander, Freixa X, Cases, Aleix, Maduell, Francisco. Percutaneous left atrial appendage closure, a safe alternative to anticoagulation for patients with nonvalvular atrial fibrillation and end-stage renal disease on hemodialysis: A single center experience. ARTIFICIAL ORGANS 2020; 44:513 - 521. ISSN 0160-564X. DOI: 10.1111/aor.13603 IF: 2.663 Q3

84.-Flores-Umanzor E, Cepas-Guillen PL, Arzamendi D, Cruz-Gonzalez I, Regueiro A, Freixa X. Rationale and design of a randomized clinical trial to compare two antithrombotic strategies after left atrial appendage occlusion: double antiplatelet therapy vs. apixaban (ADALA study). JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY 2020; 59: 471 - 477. ISSN 1383-875X. DOI: 10.1007/s10840-020-00884-x IF: 1.759 Q2

85.-Sanchis L, Freixa X, Regueiro A, Perdomo JM, Sabate M, Sitges M. Safety and outcomes of Mitra-Clip implantation in functional mitral regurgitation according to degree of left ventricular dysfunction. Rev Esp Cardiol 2020;73:530 - 535. DOI: 10.1016/j.rec.2019.06.002 IF: 7.05 Q3

86.- Flores E, Cepas P, Caldentey G, Perez-Fuentes P, Arevalos V, Ivey-Miranda J, Regueiro A, Freixa X et al. Sex-based differences in chronic total occlusion management and long-term clinical outcomes. Int J Cardiol 2020; 319:46 – 51. DOI: 10.1016/j.ijcard.2020.05.090 IF: 4.039 Q1

87.- Pascual I, Carrasco-Chinchilla F, Benito-Gonzalez T, Li Chi H, Avanzas P, Nombela-Franco L, Pan, M, Frutos A, Freixa X et al. Transcatheter Mitral Repair for Functional Mitral Regurgitation According to Left Ventricular Function: A Real-Life Propensity-Score Matched Study. JOURNAL OF CLINICAL MEDICINE 2020; 9:1792. DOI: 10.3390/jcm9061792 IF: 4.964 Q1

88.-Pascual I, Arzamendi D, Carrasco-Chinchilla F, Fernandez-Vazquez F, Freixa X et al. Transcatheter mitral repair according to the cause of mitral regurgitation: real-life data from the Spanish MitraClip registry. Rev Esp Cardiol 2020;73:643 - 651. ISSN 1885-5857 / DOI: 10.1016/j.recesp.2019.07.014 IF: 7.05 Q3

89.-Estevez-Loureiro R, Adamo M, Arzamendi D, Denti P, Freixa X et al. EREMMI Investigators. Transcatheter mitral valve repair in patients with acute myocardial infarction: insights from the European Registry of MitraClip in Acute Mitral Regurgitation following an acute myocardial infarction (EREMMI). EUROINTERVENTION 2020; 15:1248 - 1250. ISSN 1774-024X / DOI: 10.4244/EIJ-D-19-00653 IF: 6.534 Q1

90.-Garot P, Iriart X, Aminian A, Kefer J, Freixa X et al. Value of FEops HEARTguide patientspecific computational simulations in the planning of left atrial appendage closure with theAmplatzer Amulet closure device: rationale and design of the PREDICT-LAA study. OPEN HEART 2020; 7:e001326. ISSN 2053-3624 / DOI: 10.1136/openhrt-2020-001326 IF: 2.38 Q2

91.-Benito T, Freixa X, Godino C et al. Ventricular arrythmias in patients with functional mitral regurgitation and implantable cardiac devices: implications of mitral valve repair with MitraClip. Ann Transl Med 2020; 8 – 15: 956. DOI: 10.21037/atm.2020.02.45 IF: 3.932 Q1 92.-Jimenez-Britez G, Flores-Umanzor E, Freixa X. Captured in the act: Thrombus crossing patent-foramen-ovale. Revista Clinica Espanola 2019;219:344 - 345. 2019. DOI: 10.1016/j.rce.2018.10.010 IF:3.064 Q3

93.-Hernandez-Enriquez M, Chollet T, Bataille V, Campelo-Parada F, Boudou N, Bouisset F, Grunenwald E, Porterie J, Freixa X et al. Comparison of the Frequency of Thrombocytopenia After Transfemoral Transcatheter Aortic Valve Implantation Between Balloon-Expandable and Self-Expanding Valves. AMERICAN JOURNAL OF CARDIOLOGY 2019; 123:1120 - 1126. ISSN 0002-9149 DOI: 10.1016/j.amjcard.2018.12.036 IF: 2.55 Q1

94.-Gonzalez-de Paz L, Kostov B, Alvira-Balada M, Colungo C, Garcia N, Roura S, Blat E, Sierra-Benito, Cr, Sotoca-Momblona, J, Benavent-Areu J, Sanchez E, Siso-Almirall A, Serrato M, Vidiella I, Perez E, Ortega M, Porcar S, Freixa X et al.OMBP Grp. Effectiveness of a new onehour blood pressure monitoring method to diagnose hypertension: a diagnostic accuracy clinical trial protocol. BMJ OPEN 2019; 9:e0229268. ISSN 2044-6055DOI: 10.1136/bmjopen-2019-029268 IF: 2.692 Q1

95.-Lee, Oh-Hyun, Kim, Young Dae, Kim, Jung-Sun, Pak, Hui-Nam, Hong, Geu-Ru, Shim, Chi Young, Uhm, Jae-Sun,Cho, In-Jeong, Joung, Boyoung, Hong, Sung-Jin, Ahn, Chul-Min, Kim, Byeong-Keuk, Ko, Young-Guk, Choi, Donghoon, Hong, Myeong-Ki, Yu, Cheol-Woong, Lee, Hyun-Jong, Kang, Woong-Chol, Shin, Eun-Seok, Choi, Rak-kyeong, Lim, Do-Sun, Freixa X, Tzikas, Apostolos, Heo, Ji Hoe, Jang, Yangsoo, Park, Jai-Wun. Favorable neurological outcome after ischemic cerebrovascular events in patients treated with percutaneousleft atrial appendage occlusion compared with warfarin. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2019; 94:E23 - E29. ISSN 1522-1946 DOI: 10.1002/ccd.27913 IF:2,585 Q1

96.-Flores-Umanzor E, Vazquez S, Cepas-Guillen, Pedro, Ivey-Miranda, Juan, Caldentey, Guillem,Jimenez-Britez, Gustavo, Regueiro, Ander, Freixa X et al. Impact of revascularization versus medical therapy alone for chronic total occlusion management in older patients. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2019; 94:527 - 535. ISSN 1522- 1946 DOI: 10.1002/ccd.28163 IF:2.585 Q1

97.-Aguado A, Olivares A L, Yague C, Silva E, Nunez-Garcia M, Femandez-Quilez A, Mill J, Genua I, Arzamendi D, De Potter T, Freixa X, Camara O. In silico Optimization of Left Atrial Appendage Occluder Implantation Using Interactive and Modeling Tools. FRONTIERS IN PHYSIOLOGY 2019; 10:237. ISSN 1664-042X / DOI: 10.3389/fphys.2019.00237 IF: 4.755 Q1

98.-Freixa X, Cruz-Gonzalez I, Regueiro A, Nombela-Franco L et al. Left Atrial Appendage Occlusion as Adjunctive Therapy to Anticoagulation for Stroke Recurrence. JOURNAL OF INVASIVE CARDIOLOGY 2019; 31:212 - 216. ISSN 1042-3931 IF: 2.3 Q2

99.-Ortega-Paz L, Regueiro A, Perdomo J, Sanchis L, Sabate M, Freixa X. Minimally Invasive Transradial Percutaneous Closure of an Aortic Paravalvular Leak After Transcatheter Aortic Valve Replacement. CANADIAN JOURNAL OF CARDIOLOGY 2019; 35:941e1 - 941e2. ISSN 0828-282X.DOI: 10.1016/j.cjca.2019.04.025 IF: 6.614 Q1

100.-Jimenez Britez G, Sanchis L, Regueiro A, Sabate M, Sitges M, Freixa X. Minimally invasive Transesophageal Echocardiography for Left Atrial Appendage Occlusion With a Latest-generation Microprobe. Initial Experience. Rev Esp Cardiol 2019; 72: 511 - 512. ISSN 1885-5857 DOI: 10.1016/j.rec.2018.05.016 IF: 7.05 Q3

101.-Flores-Umanzor E, Cepas-Guillen Pedro L, Freixa X. Percutaneous Closure of a Left Ventricular Outflow Tract Pseudoaneurysm. Rev Esp Cardiol 2019; 72:164 ISSN 1885-5857. DOI: 10.1016/j.recesp.2018.02.004 IF: 7.05 Q3

102.-Freixa X, Regueiro A. Role and Assessment of Peri-Device Leaks After Left Atrial Appendage Occlusion. CANADIAN JOURNAL OF CARDIOLOGY 2019; 35:370 - 372. ISSN 0828- 282X DOI: 10.1016/j.cjca.2019.01.015 IF: 6.614 Q1

103.- Hernandez-Enriquez M, Regueiro A, Romaguera R, Andrea R, Gomez-Hospital A, Joan, Pujol-Lopez M, Ferreiro-Gutierrez, J, Brugaletta S, Roura G, Freixa X et al. Thrombocytopenia after transcatheter aortic valve implantation. A comparison between balloon-expandable and self-expanding valves. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2019; 93:1344 - 1351. ISSN 1522-1946 / DOI: 10.1002/ccd.27907 IF:2.585 Q1

104.-Garcia J, Jimenez-Britez G, Flores-Umanzor E, Mendieta G, Freixa X, Sabate M. Thrombotic and Bleeding Events After Percutaneous Coronary Intervention in Out-of hospital Cardiac Arrest With and Without Therapeutic Hypothermia. Rev Esp Cardiol 2019:72: 433 - 435. ISSN 1885-5857 DOI: 10.1016/j.rec.2018.04.022 IF: 7.05 Q3

105.- Regueiro A, Fernandez-Rodriguez D, Freixa X, Bosch X, Martin-Yuste V, Brugaletta S, Roque M, Sabate M, Masotti M. False Positive STEMI Activations in a Regional Network: Comprehensive Analysis and Clinical Impact. Results From the Catalonian Codi Infart Network. Rev Esp Cardiol 2018;71:243 - 249. ISSN 1885-5857 DOI: 10.1016/j.recesp.2017.05.025 IF: 7.05 Q3

106.-Nombela-Franco L, Rodes-Cabau J, Cruz-Gonzalez I, Freixa X et al. Incidence, Predictors and Prognostic Value of Acute Kidney Injury Among Patients Undergoing Left Atrial Appendage Closure. JACC-CARDIOVASCULAR INTERVENTIONS 2018; 11:1074 - 1083. ISSN 1936-8798 / DOI: 10.1016/j.jcin.2018.03.022 IF:11.075 Q1

107.-Cruz-Gonzalez I, Freixa X, Fernandez-Diaz J, Moreno-Samos C, Martin-Yuste V, Goicolea J. Left Atrial Appendage Occlusion With the LAmbre Device: Initial Experience. Rev Esp Cardiol 2018; 71:755 - 756. ISSN 1885-5857 / DOI: 10.1016/j.recesp.2017.02.023 IF: 7.05 Q3

108.-Hernandez-Enriquez M, Freixa X, Quintana E, Pereda D, Sandoval E, Sabate M. Paravalvular Leak Correction: Searching for a Balance Between Surgical and Percutaneous Techniques. Rev Esp Cardiol 2018;71:679-681. ISSN 1885-5857 / DOI: 10.1016/j.recesp.2017.03.034 IF: 7.05 Q3

109.-Tarantini G, D'Amico G, Latib A, Montorfano M, Mazzone P, Fassini G, Maltagliati A, Ronco F, Sacca, Brugaletta S, Cruz-Gonzalez I, Ibrahi R, Freixa X. Percutaneous left atrial appendage occlusion in patients with atrial fibrillation and left appendage thrombus: feasibility, safety and clinical efficacy. EUROINTERVENTION 2018; 13:1595 - 1602. ISSN 1774- 024X DOI: 10.4244/EIJ-D-17-00777 IF: 7.728 Q1

110.-Garcia-Isla G, Olivares A, Silva E, Nunez-Garcia M, Butakoff C, Sanchez-Quintana D, Morales H, Freixa X, Noailly J, De Potter T, Camara O. Sensitivity analysis of geometrical parameters to study haemodynamics and thrombus formation in the left atrial appendage. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. DOI: 10.1002/cnm.3100 IF: 2.138 Q2

111.-Freixa X, Hernandez-Enriquez M, Sanchis L, Regueiro A, Sabate M, Sitges M. Tricuspid Percutaneous Repair With the MitraClip System: First Implant in Spain. Rev Esp Cardiol 2018;71:976 - 977. ISSN 1885-5857 / DOI: 10.1016/j.rec.2017.08.006 IF: 7.05 Q3

112.-Sharma S, Kotowycz MA, Sharma V, Choudhury A, Chan W, Freixa X, Dzavik V, Overgaard CB. Characteristics and outcomes of patients undergoing percutaneous coronary intervention within 1 year of coronary artery bypass graft surgery. Catheterization Cardiovascular Intervention 2017; 90:186 - 193. DOI: 10.1002/ccd.26853 IF:2.585 Q1

113.-Lempereur M, Aminian A, Freixa X, Gafoor S, Kefer J, Tzikas A, Legrand V, Saw J. Device-Associated Thrombus Formation after Left Atrial Appendage Occlusion: A Systematic Review of Events Reported with the Watchman, the Amplatzer Cardiac Plug and the Amulet. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 2017;90:E111 - E121. ISSN 1522- 1946 DOI: 10.1002/ccd.26903 IF:2.585 Q1

114.-Flores EJ, Hernandez-Enriquez M, Jimenez-Britez G, San Antonio R, Freixa X. Emergencypercutaneous embolization of iatrogenic right coronary artery-pleural space communication. Acta Cardiol 2017; 72:349 - 350. DOI: 10.1080/00015385.2017.1305184 IF: 1.718 Q3

115.-Brugaletta S, Scalone G, Dantas AP, Ortega-Paz L, Garabito M, Roque M, Martin V, Masotti M, Freixa X, Sabate M. Endothelial function impairment in STEMI patients with out of hospital cardiac arrest under therapeutic hypothermia treatment. International of Journal of Cardiology 2017; 232:70 - 75. DOI: 10.1016/j.ijcard.2017.01.050 IF:4.039 Q1

116.-Fernandez-Rodriguez D, Regueiro A, Cevallos J, Bosch X, Freixa X et al., Invest Registro Codi Infart. Gender gap in medical care in ST segment elevation myocardial infarction networks: Findings from the Catalan network Codi Infart. MEDICINA INTENSIVA 2016;41: 70 - 77. ISSN 0210-5691 / DOI: 10.1016/j.medin.2016.06.008 IF: 2.799 Q2

117.- Saw J, Tzikas A, Shakir S, Gafoor S, Omran H, Nielsen-Kudsk JE, Kefer J, Aminian A, Berti S, Santoro G, Nietlispach F, Moschovitis A, Cruz-Gonzalez I, Stammen F, Tichelbacker T, Freixa X. Incidence and clinical impact of device associated thrombus and peri-device leakfollowing left atrial appendage closure with the Amplatzer cardiac plug. JACC Cardiovascular Interventions 2017; 10:391 - 399 / DOI: 10.1016/j.jcin.2016.11.029 IF:11.075 Q1

118.-Freixa X, Estevez-Loureiro R, Carrasco-Chinchilla F, Arzamendi D, Jimenez-Quevedo P, Nombela-Franco L, Cruz-Gonzalez I, Amat-Santos IJ, Sabate M. Initial Results of CombinedMitraClipAR Implantation and Left Atrial Appendage Occlusion. The Journal of heart valve disease 2017;26:169 - 174. ISSN 0966-8519 IF: 0.5 Q2

119.-Lempereur M, Aminian A, Freixa X, Gafoor S, Shakir S, Omran H, Berti S, Santoro G et al. Left atrial appendage occlusion in patients with atrial fibrillation and previous major gastrointestinal bleeding (from the Amplatzer cardiac plug multicenter registry). American Journal of Cardiology 2017; 120:414 - 420. DOI: 10.1016/j.amjcard.2017.04.046 IF:3.133 Q1

120.- Cruz-Gonzalez I, Freixa X, Fernandez-Diaz JA, Moreno-Samos JC, Martin-Yuste V, Goicolea J. Left atrial appendage occlusion with the Lambre Device: Initial experience. Rev Esp Cardiol 2018;71:755-756. DOI: 10.1016/j.rec.2017.04.015 IF: 7.05 Q3

121.-Jimenez-Britez G, Freixa X, Flores-Umanzo E, San Antonio R, Caixal G et al. Out-oof hospital cardiac arrest and stent thrombosis: Ticagrelor versus clopidogrel in patients with primary percutaneous coronary intervention under mild therapeutic hypothermia. RESUSCITATION 2017;114:141 – 145. ISSN 0300-9572 / DOI: 10.1016/j.resuscitation.2017.02.015 IF: 6.251 Q1

122.-Garcia E, Arzamendi D, Jimenez-Quevedo P, Sarnago F, Marti G, Sanchez-Recalde A, Lasa-Larraya G, Sancho M, Iniguez A, Goicolea J, Garcia San Roman K, Alonso-Briales JH, Molina E, Calabuig J, X Freixa, Berenguer A, Valdes-Chavarri M, Vazquez N, Diaz JF, Cruz- Gonzalez I. Outcomes and predictors of success and complications for paravalvular leak closure: an analysis of the Spanish real-world paravalvular leaks closure (HOLE) registry. Eurointervention 2017;12:1962 - 1968. DOI: 10.4244/EIJ-D-16-00581 IF: 7.728 Q1

123.-Tzikas Apostolos, Freixa X, Llull L, Gafoor et al. Patients with intracranial bleeding and atrial fibrillation treated with left atrial appendage occlusion: Results from the Amplatzer Cardiac Plug registry. INTERNATIONAL JOURNAL OF CARDIOLOGY 2017; 236:232 - 236. ISSN 0167-5273 / DOI: 10.1016/j.ijcard.2017.02.042 IF: 1.33 Q1

124.- Carrasco-Chinchilla F, Estevez-Loureiro R, Andraka L, Arzamendi D, Freixa X, Suarez de Lezo J. Percutaneous Mitral Repair With MitraClip in Patients Treated With Transcatheter Aortic Valve Implantation. Rev Esp Cardiol 2017;70:1144 - 1145. ISSN 1885-5857 / DOI: 10.1016/j.recesp.2016.12.005 IF: 7,05 Q3

125.- Freixa X, Panaro A, Carballo J. Percutaneous closure of a whale tail left atrial appendage. Rev Esp Cardiol 2017;70:770. http://dx.doi.org/10.1016/j.rec.2016.12.004 IF: 7,05 Q3

126.-Ishida K, Otsuki S, Giacchi G, Ortega-Paz L, Shiratori Y, Freixa X et al. Serial optical coherence tomography assessment of malapposed struts after everolimus-eluting stent implantation. A subanalysis from the HEAL-EES study. CARDIOVASCULAR REVASCULARIZATION MEDICINE 2017; 18:47 - 52. ISSN 1553-8389 DOI: 10.1016/j.carrev.2016.08.010 IF: 1.168 Q3

127.-Hernandez-Enriquez M, Brugaletta S, Andreu D, Macia-Munoz G, Castrejon-Subira M, Fernandez-Suelves S, Hernandez-Obiols M, Dantas AP, Freixa X, Martin-Yuste V, Sabate M. Three dimensional printing of an aortic model for transcatheter aortic valve implantation: possible clinical applications. International Journal of Cardiovascular Imaging 2017;33: 283 - 285. DOI: 10.1007/s10554-016-0983-0 IF: 2.316 Q2

128.-Pan M, Musumeci G, Tarantini G, Melica B, Campante-Teles R, Perez de Prado A, Arzamendi D, Freixa X, Estevez-Loureiro R. Transcatheter mitral valve interventions for mitral regurgitation, with special focus on MitraClip: The position of Spanish, Portuguese and Italian Interventional societies. International Journal of Cardiology2017; 243:169 - 173. DOI: 10.1016/j.ijcard.2017.05.029 IF: 4.039 Q1

129.-Freixa X, Llull L, Gafoor S, Cruz-Gonzalez I, Shakir S, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Kanagaratnam P, Nietlispach F, Gloekler S, Aminian A, Danna P, Rezzaghi M, Stock F, Stolcova M, Paiva L, Costa M et al. Characterization of Cerebrovascular Events After Left Atrial Appendage Occlusion. AMERICAN JOURNAL OF CARDIOLOGY 2016; 118:1836 - 1841. ISSN 0002-9149 96. DOI: 10.1016/j.amjcard.2016.08.075 IF:3.133 Q1

130.-Freixa X, Gafoor S, Regueiro A, Cruz-Gonzalez I, Shakir S, Omran H, Berti S et al. Comparison of Efficacy and Safety of Left Atrial Appendage Occlusion in Patients Aged &lt,75 to ≥75 Years. American Journal of Cardiology 2016;117: 84 - 90. ISSN 00029149 / DOI: 10.1016/j.amjcard.2015.10.024 IF:3.133 Q1

131.-Gomez-Lara J, Brugaletta S, Jacobi F, Ortega-Paz L, Nato M, Roura G, Romaguera R, Ferreiro, J, Teruel L, Gracida M, Martin-Yuste V, Freixa X et al. Five-Year Optical Coherence Tomography in Patients With ST-Segment-Elevation Myocardial Infarction Treated With Bare-Metal Versus Everolimus-Eluting Stents. CIRCULATION-CARDIOVASCULAR INTERVENTIONS 2016; 9:e003670. ISSN 1941-7640 DOI: 10.1161/CIRCINTERVENTIONS.116.003670 IF: 6.546 Q1

132.-Kefer J, Tzikas A, Freixa X et al. Impact of chronic kidney disease on left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation. INTERNATIONAL JOURNAL OF CARDIOLOGY 2016; 207: 335 -340. ISSN 0167-5273 DOI: 10.1016/j.ijcard.2016.01.003 IF: 4.039 Q1

133.-Ferreira-Gonzalez I, Carrillo X, Martin V, de la Torre Hernandez Jose M, Baz JA, Navarro Manchon J, Masotti M, Cequier A, Cardenas M, Manterola F, ACDC Res Grp. Interhospital Variability in Drug Prescription After Acute Coronary Syndrome: Insights From the ACDC Study. Rev Esp Cardiol 2016; 69:117 - 124. ISSN 1885-5857 / DOI: 10.1016/j.rec.2015.04.018 IF: 7,05 Q3

134.-Hernandez-Enriquez M, Ascaso M, Freixa X, Sandoval E, Giacchi G, Brugaletta S, Martin- Yuste V, Quintana E, Sabate M. Late Right Coronary Ostium Occlusion After Percutaneous Aortic Paravalvular Leak Closure: Immediate Results Do Not Always Predict Long- Term Performance. JOURNAL OF INVASIVE CARDIOLOGY 2016; 28:E69 - E70. ISSN 1042-3931 IF:2.022 Q2

135.-Jimenez-Britez G, Freixa X, Flores E, Penela D, Hernandez-Enriquez M, San Antonio R, Caixal G, Garcia J, Roque M, Martin V, Brugaletta S, Masotti M, Sabate M. Safety of glycoprotein IIb/IIIa inhibitors in patients under therapeutic hypothermia admitted for an acute coronary syndrome. RESUSCITATION 2016; 106: 102 - 112. ISSN 0300-9572 DOI: 10.1016/j.resuscitation.2016.06.031 IF: 6.251 Q1

136.-Otsuki S, Brugaletta S, Sabate M, Shiratori Y, Gomez-Monterrosas O , Scalone G, Romero-Villafane, S, Hernandez-Enriquez M, Freixa X, Martin-Yuste V, Masotti M. Overtime evaluation of the vascular HEALing process after everolimus-eluting stent implantation by optical coherence tomography. The HEAL-EES study. CARDIOVASCULAR REVASCULARIZATION MEDICINE 2016; 17:241 - 247. ISSN 1553-8389 DOI: 10.1016/j.carrev.2016.02.006 IF: 1.168 Q3

137.-Tzikas A, Gafoor S, Meerkin D. Freixa X, Cruz-Gonzalez I, Lewalter T, Saw J, Berti S, Nielsen-Kudsk JE, Ibrahim R, Lakkireddy D, Paul V, Arzamendi D, Nietlispach F, Worthley S, Hildick-Smith D. Benoit J, Tondo C, Aminian A, Kalarus Z, Schmidt B, Sondergaard L, Keffer J, Meire B, Park JW, Sievert H,Omran H. Left Atrial Appendage Occlusion with the Amplatze Amulet device: An expert consensus step-by-step approach. Eurointervention 2016; 1512 - 1521. 2. ISSN 1774-024X. DOI: 10.4244/EIJV11I13A292 IF: 7.728 Q1

138.-Kefer J, Tzikas A, Freixa X, Shakir S, Gafoor S, Nielsen-Kudsk JE, Berti S, Santoro G, Aminian A, Landmesser U, Fabian Nietlispach F, Ibrahim R, Danna P, Benit E, Budts W, Stammen F, De Potter T, Tichelbacker T, Gloekler S, Kanagaratnam P, Costa M, Cruz-Gonzalez I, Sievert H, Schillinger W, Park JW, Meier B, Omran H. Impact of Chronic Kidney Disease on Left Atrial Appendage Occlusion for Stroke Prevention in Patients with Atrial Fibrillation. Int J Cardiol 2016 ; 207 :335-40 IF: 4.164 Q1

139.-Abualsaud A, Freixa X, Tzikas A, Chan J, Garceau P, Basmadjian A, Ibrahim R. Side by side comparison of LAA Occlusion performance with the Amplatzer Cardiac Plug and Amplatzer Amulet. J Invasiv Cardiol. 2016 ;1:34-8 . IF : 2.022 Q2

140.-Trilla M, Freixa X, Regueiro A, Fernandez-Rodriguez D, Brugaletta S, Martin-Yuste V, Jimenez M, Betriu A, Sabate M, Masotti M. Impact og Aging on Radial Spasm During Coronary Catheterization. J Invasive Cardiol. 2015 Dec,27(12): E303-7 IF: 2.022 Q2 141.-Freixa X, Gafoor S, Regueiro A, Cruz-Gonzalez I, Shakir S, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Sievert H, Kanagaratnam P, Nietlispach F, Gloekler S, Aminian A, Danna P, Rezzaghi M, Stock F, Stolcova M, Costa M, Ibrahim R, Schillinger W, Park JW, Meier B, Tzikas A. Comparison of Efficacy and Safety of Left Atrial Appendage Occlusion in Patients Aged <75 to ≥75 Years. Am J Cardiol. 2016 Jan 1,117(1):84-90 IF:3.133Q1

142.-Freixa X, Regueiro A, Neves de Araujo G, Leal N, Sabate M. Double atrial septum or redundant Eustachian valve: procedural management during atrial septal defect occlusion. EuroIntervention. 2015 Oct 22,11(6):e1-2. IF: 7.728 Q1

143.-Raber L, Brugaletta S, Yamaji K, O'Sullivan CJ, Otsuki S, Koppara T, Taniwaki M, Onuma Y, Freixa X, Eberli FR, Serruys PW, Joner M, Sabate M, Windecker S. Very Late Scaffold Thrombosis: Intracoronary Imaging and Histopathological and Spectroscopic Findings. J Am Coll Cardiol. 2015 Oct 27,66(17):1901-14. IF:24.094 Q1

144.-Freixa X, Hernandez M, Farrero M, Sitges M, Jimenez G, Regueiro A, Fita G, Tatjer I, Andrea R, Martin-Yuste V, Brugaletta S, Masotti M, Sabate M. Levosimendan as an adjunctive therapy to MitraClip implantation in patients with severe mitral regurgitation and left ventricular dysfunction. Int J Cardiol. 2015 Sep 25,202:517-518. IF: 4.039 Q1

145.-Estevez-Loureiro R, Arzamendi D, Freixa X, Cardenal R, Carrasco-Chinchilla F, Serrador- Frutos A, Pan M, Sabate M, Diaz J, Hernandez JM, Serra A, Fernandez-Vazquez F, Spanish Working Group on MitraClip. Percutaneous Mitral Valve Repair for Acute Mitral Regurgitation After an Acute Myocardial Infarction. J Am Coll Cardiol. 2015 Jul 7,66(1)91-2. IF:24.094 Q1

146.-Freixa X, Scalone G, Martin-Yuste V, Vidal B. Large protruding thrombus over left atrial appendage occlusion device successfully treated with apixaban. Eur Heart J. 2015 Jun 14,36(23):1427 IF: 29.983 Q1

147.-Regueiro A, Cuadrado-Godia E, Bueno-Beti C, Diaz-Ricart M, Oliveras A, Novella S, Gene GG, Jung C, Subirana I, Ortiz-Perez JT, Roque M, Freixa X, Nunez J, Escolar G, Marrugat J, Hermenegildo C, Valverde MA, Roquer J, Sanchis J, Heras M. Mobilization of endotelial progenitor cells in acute cardiovascular events in the PROCELL study: time-course after acute myocardial infarction and stroke. J Mol Cell Cardiol. 2015 Mar,80:146-55. IF:5.763 Q1

148.-Tzikas A, Shakir S, Gafoor S, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Cruz-Gonzalez I, Sievert H, Tichelbacker T, Kanagaratnam P, Nietlispach F, Aminian A, Kasch F, Freixa X, Danna P, Rezzagh M, Vermeersch P, Stock F, Stolcova M, Costa M, Ibrahim R, Schillinger W, Meier B, Park JW. Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicentre experience with the AMPLATZER Cardiac Plug. EuroIntervention. 2015 Jan 22,10(10). IF: 7.728 Q1

149.-Kotowycz MA, Khan SQ, Freixa X, Ivanov J, Seidelin PH, Overgaard CB, Džavik V. Rotational atherectomy through the radial artery is associated with similar procedural success when compared with the transfemoral route. Coron Artery Dis. 2015 May,26(3):254- 8. IF: 3.2 Q1

150.-Regueiro A, Freixa X, Fernandez-Rodriguez D, Diaz-Ricart M, Escolar G, Martin-Yuste V, Brugaletta S, Sabate M, Masotti M. Platelet reactivity assessment with VerifyNowR: substitute or complement for light transmission aggregometry?. Int J Cardiol. 2015 Jan 15,178:221-2. IF: 4.039 Q1

151.-Regueiro A, Fernandez-Rodriguez D, Brugaletta S, Martin-Yuste V, Masotti M, Freixa X, Cequier A, Iniguez A, Serruys PW, Sabate M, EXAMINATION trial investigators. Sex-related Impact on Clinical Outcome of Everolimus-eluting Versus Bare-metal Stents in ST-segment Myocardial Infarction. Insights From the EXAMINATION Trial. Rev Esp Cardiol (Engl Ed). 2015 May,68(5):382-9. IF: 7.05 Q3

152.-Fernandez-Rodriguez D, Martin-Yuste V, Feu F, Brugaletta S, Freixa X, Regueiro A, Sabate M. Can the vicious cycle of obscure or intractable gastrointestinal bleeding be broken in patients with atrial fibrillation subject to anticoagulant therapy? Rev Esp Enferm Dig. 2014 May,106(5):350-3. IF:2.086 Q3

153.-Scalone G, Brugaletta S, Garcia-Garcia HM, Martin-Yuste V, Azpeitia Y, Otsuki S, Gomez O, Freixa X, Masotti M, Sabate M. Frequency and predictors of thrombus inside the guiding catheter during interventional procedures: an optical coherence tomography study. Int J Cardiovasc Imaging. 2015 Feb,31(2):239-46 IF:2.316 Q2

154.-Freixa X, Chan J, Bonan R, Ibrahim R, Lamarche Y, Demers P, Basmadjian A, Ibrahim R, Cartier R, Asgar AW. Impact of coronary artery disease on left ventricular ejection fraction recovery following transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2015 Feb 15,85(3):450-8 IF:2.585 Q1

155.-Freixa X, Hayami D, Basmadjian A, Asgar AW. MitraClip repair of a "trileaflet" regurgitant mitral valve. EuroIntervention. 2015 Jul,11(3):355. IF: 7.728 Q1

156.-Regueiro A, Freixa X, Bartolome Y, Postigo C, Sales S, Falco J. Successful percutaneous treatment of an arteriovenous fistula after radial primary percutaneous coronary intervention. JACC Cardiov Interv. 2014 Sep,7(9):e123-4. IF:11.075 Q1

157.-Darsaklis D, Freixa X, Asgar A, Ibrahim R, Basmadjian A, Deguise P, Garceau P. A novel system for transcatheter closure of patent foramen ovale: clinical and echocardiographic outcome comparison with other contemporary devices. Can J Cardiol. 214 Jun 30: 639-46. IF:6.614 Q1

158.-Freixa X, Abualsaud A, Chan J, Nosair M, Tzikas A, Garceau P, Basmadjian A, Ibrahim R. Left atrial appendage occlusion: Initial experience with the Amplatzer Amulet. Int J Cardiol. 2014 Jul 1,174(3):492-6. IF: 4.039 Q1

159.-Freixa X, Andrea R, Martin-Yuste V, Fernandez-Rodriguez D, Brugaletta S, Masotti M, Sabate M. Cardiac embolism after implantable cardiac defibrillator shock in nonanticoagulated atrial fibrillation: The role of left atrial appendage occlusion. World J Cardiol. 2014 Apr 26,6(4)213-5. IF: 1.67 Q3

160.-Hernandez-Enriquez M, Freixa X. Current Indications for Percutaneous Closure of Patent Foramen Ovale. Rev Esp Cardiol. 2014 Aug,67(8):603-7. IF: 7.05 Q3

161.-Cevallos J,Andrea R, Falces C, Martin-Yuste V, Freixa X, Vidal B, Brugaletta S, Castella M, Masotti M, Sabate M. Transcatheter aortic valve implantation in patients with left main percutaneous coronary intervention. J Heart Valve Dis. 2013 Nov,22(6):874-7 IF: 0.5 Q3

162.-Regueiro A, Freixa X, Heras M, Penela D, Fernandez D, Brugaletta S, Martin-Yuste V, Masotti M, Sabate M. Impact of coronary hypothermia on coronary flowInt J Cardiol. Int J Cardiol. 2014 Mar 1,172(1):228-9 IF: 4.039 Q1

163.-Freixa X, Arzamendi D, Tzikas A, Noble S, Basmadjian A, Garceau P, Ibrahim R. Cardiac Procedures to prevent stroke: PFO closure /LAAA occlusion. Can J Cardiol. 2014 Jan,30(1):87- 95 IF : 6.614 Q1

164.-Freixa X, Ibrahim R, Chan J, Garceau P, Dore A, Marcotte F, Mercier LA, Mongeon FP, Basmadjian A, Khairy P, Asgar A. Initial clinical experience with the GORE septal occlude for the treatment of atrial septal defects and patent foramen ovale. Eurointervention. 2013 Sep,9(5):629-35. IF: 7.728 Q1

165.-Freixa X, Martin-Yuste V. Percutaneous left atrial appendage occlusion. Rev Esp Cardiol. 2013 Dec,66(12):919-22. IF: 7.05 Q3

166.-Freixa X, Tzikas A, Basmadjian A, Garceau P, Ibrahim R. The Chicken Wing morphology: an anatomical challenge for lefta atrial appendage occlusion. J Interv Cardiol. 2013 Oct,26(5):509-14. IF: 1.73 Q2

167.-Tzikas A, Ibrahim R Velasco D, Freixa X, Alburquenque M, Khairy P, Bass JL, Ramirez J, Aguirre D, Miro J. Transcatheter closure of perimembraneous ventricular septal defect with the Amplatzer membranous VSD occlude 2: Initial world experience and one-year follow up. Catheter Cardiovasc Interv. 2014 Mar 1,83(4):571-80. IF:2,585 Q1

168.-Freixa X, Gallo R. Internal thoracic artery dissection: a proposed mechanistic explanation. JACC Cardiovasc Interv. 2013 May,6(5):533-4. IF:11,075 Q1

169.-Urena M, Rodes-Cabau J, Freixa X, Saw J, Webb JG, Freeman M, Hrlick E, Osten M, Chan A, Marquis JF, Champagne J, Ibrahim R. Percutaneous left atrial appendage closure with the ACP device in patients with nonvalvular atrial fibrillation and contraindications to anticoagulation therapy. J Am Coll Cardiol. 2013 Jul 9,62(2):96-102. IF:24,094 Q1

170.-Freixa X, Chan J, Tzikas A, Garceau P, Basmadjian A, Ibrahim R. Percutaneous closure of a very large left atrial appendage using the Amplatzer Amulet. Can J Cardiol. 2013

Oct,29(10):1329.e9-1329.e11 IF: 6.614 Q1

171.-Fernandez D, Cevallos J, Brugaletta S, Martin-Yuste V, Freixa X, Andrea R, Falces C, Regueiro A, Masotti M, Sabate M. Percutaneous transcatheter aortic valve implantation: present and future perspective. Expert Rev Med Devices. 2013 Mar,10(2):185-99. IF: 3.166 Q2

172.-Freixa X, Belle L, Joseph L, Tanguay JF, Souteyrand G, L´Allier PL, Jolicoeur EM. Immediate vs. delayed stenting in acute myocardial infarction: as systemic review and metanalysis. Eurointervention. 2013 Feb. 2013 Feb 22,8(10):1207-16 IF: 7.728 Q1

173.-Freixa X, Chan JL, Tzikas A, Garceau P, Basmadjian A, Ibrahim R. The Amplatzer™ Cardiac Plug 2 for left atrial appendage occlusion: novel features and first-in-man experience. EuroIntervention. 2013 Jan 22,8(9):1094-8 IF: 7.728 Q1

174.-Freixa X, Tzikas A, Sobrino A, Chan J, Basmadjian AJ, Ibrahim R. Left atrial appendage closure with the Amplatzer™ Cardiac Plug: Impact of shape and device sizing on follow-up leaks. Int J Cardiol. 2013 Sep 30,168(2):1023-7. IF: 4.164 Q1

175.-Freixa X, Bonan R, Asgar AW. Unusual Coronary Occlusion Post Transcatheter Aortic Implantation: The Importance of Clinical Assessment. Can J Cardiol. 2013 Aug. 29(8):1014 IF: 6.614 Q1

176.-Freixa X, Almasood AA, Asif N, Bui S, Ivanov J, Osten MD, Ing D, Overgaard CB, Horlick E, Seidelin PH, Džavik V. Long-term outcomes using a two-stent technique for the treatment of coronary bifurcations. Int J Cardiol. 2013 Sep 20,168(1):446-51 IF: 4.039 Q1

177.-Freixa X, Garceau P, Asgar A. First experience with the new GoreR septal occluder for the closure of multiple atrial septal defects. Catheter Cardiovasc Interv. 2013 Jun 1,81(7):1238-42. IF:2.585 Q1

178.-Freixa X, Portillo K, Pare C, Garcia-Aymerich J, Gomez, F, Benet M, Roca J, Farrero E, Ferrer J, Fernandez-Palomeque C, Anto JM, Barbera JA. Echocardiographic abnormalities in patients with COPD at their first hospital. Eur J Resp. 2013 Apr,41(4):784-91. IF: 33.8 Q1

179.-Ho KW, Ivanov J, Overgaard C, Osten M, Freixa X, Ing D, Horlick E, Mackie K, Seidelin P, Dzavik V. Anticoagulation with dual antiplatelet therapy after coronary stenting in patients with nonvalvular atrial fibrillation. Can J Cardiol. 2013 Feb,29(2):213-8. IF: 6.614 Q1

180.- Freixa X, Dzavik V, Forman S, Rankin J, Buller C, Cantor W, Ruzyllo W, Reynolds H, Lamas G, Hochman J. Long Term Outcomes Following a Strategy of PCI of the Infarct-related Artery with DES or BMS vs. Medical Therapy Alone In The Occluded Artery Trial (OAT). Am Heart J. 2012 Jun,163(6):1011-8. IF: 2.778 Q1

181.-Freixa X, Carpen M, Kotowycz M, Ho KW, Krimly A, Osten M, Overgaard, M, Horlick E, Seidelin P, Davik V. Long-term outcomes after percutaneous intervention of the internal thoracic artery anastomosis: the use of drug-eluting stents is associated with a higher need of repeat revascularization. Can J Cardiol. 2012 Jul-Aug,28(4):458-63. IF: 6.614 Q1

182.-Freixa X, Almasood A, Khan S, Osten M, Ing D, Overgaard C, Horlick E, Seidelin P, Dzavik V. Choice of stent and outcomes after treatment of drug-eluting stent restenosis in highly complex lesions. Catheter Cardiovasc Interv. 2013 Jan 1,81(1) IF:2.585 Q1

183.-Freixa X, Trilla M, Feldman M, Jimenez M, Betriu A, Masotti M. Right versus left transradial approach for coronary catheterization in octogenarian patients. Catheter Cardiovasc Interv. 2012 Aug 1,80(2):267-72 IF:2.585 Q1

184.-Freixa X, Bellera N, Ortiz-Perez JT, Jimenez M, Pare C, Bosch X, De Caralt TM, Betriu A, Masotti M. Ischaemic postconditioning revisited: lack of effects on infarct size following primary percutaneous coronary intervention. Eur Heart J. 2012 Jan,33(1):103-12. IF: 29.983 Q1

185.-Freixa X, Almasood A, Khan S, Wainstein R, Osherov A, Mackie K, Seidelin P, Dzavik V. Decreased risk of stent fracture-related restenosis between paclitaxel-eluting stents and sirolimus eluting stents: Results of long-term follow-up. Catheter Cardiovasc Interv. 2012 Mar 1,79(4):559-65 IF:2.585 Q1

186.-Freixa X, Masotti M, Palomo M, Diaz-Ricart M, Escolar G, Guasch E, Regueiro A, Jimenez M, Betriu A, Heras M. Endothelin-1 levels predict endothelial progenitor cell mobilization after actue myocardial infarction. Microvasc Res. 2011 Sep,82(2):177-81. IF: 3.75 Q2

187.-Wang W, Wainstein R, Freixa X, Dzavik V, Fyles A. Quantitative coronary angiography findings of patients who received previous breast radiotherapy. Radiother Oncol. 2011 Aug,100(2):184-8. IF: 6.28 Q1

188.-Garcia-Aymerich J, Gomez F, Benet M, Farrero E, Basagana X, Gayete A, Pare C, Freixa X, Ferrer J, Ferrer A, Roca J, Galdiz J, Sauleda J, Monso E, Gea J, Barbera JA, Agusti A, Anto JM. Identification and prospective preliminary validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes. Thorax. Thorax. 2011 May,66(5):430-7. IF: 9.203 Q1

189.-Freixa X, Heras M, Ortiz JT, Argiro S, Guasch E, Doltra A, Jimenez M, Betriu A, Masotti M. Usefulness of endothelin-1 assessment in acute myocardial infarction. Rev Esp Cardiol. 2011 Feb,64(2):105-10. IF: 7.05 Q3

190.-Freixa X, Sions A, Castel A, Guasch E, Loma-Osorio P, Arzamendi D, Roig E, Perez-Villa F. Low troponin-I levels on admission are associated with worse prognosis in patients with fulminant myocarditis. Transplant Prc. 2009. 416(6):2234-6. IF: 1.066 Q3

191.-Balcells E, Anto JM, Gea J et al, PAC-COPD Study Group (Freixa X). Characteristics of patients admitted for the first time for COPD exacerbation. Respir Med. 2009,103(9):1293-302. IF: 4.582 Q1

192.-Garcia-Aymerich J, Serra I, Gomez FP et al., PAC-COPD Study Group (Freixa X). Physical activity and clinical and functional status in COPD. Chest 2009, 136(1):62-70. IF: 11.393 Q1

193.-Guasch E, Sionis A, Reverter JC, Andrea R, Loma-Osorio P, Freixa X, Heras M. Safety issues of adjunctive clopidogrel in patients discharged after percutaneous coronary intervention with stent placement and requiring oral anticoagulation. Int J Cardiol. 2011 Jan 7,146(1):e1-4. IF: 4.039 Q1

194.-Benito B, Brugada R, Prich RM, Lizotte E, Cinca J, Mont L, Berruezo A, Tolosana JM, Freixa X, Brugada P, Brugada J. A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation. Heart Rhythm. 2008 Oct, 5 (10):1434-40. IF: 6.779 Q1

195.-Freixa X, Berruezo A, Magnani S, Mont Ll, Tolosana J.M, Benito B, Brugada J. Characterization of right atrial appendage tachycardia. Europace. 2008 Jan,10 (1):105-9 IF: 5.486 Q1

196.-Congiu S, Josa M, Freixa X, Azqueta M, Mestres CA, Mulet J. Mitral insufficiency with double orifice mitral valve in an adult patient. J Thorac Cardiovasc Surg. 2007 Jul,134(1):250-1 IF: 6.439 Q1

197.-Freixa X, Sitges M, Pare C. Images in cardiology. Left ventricular pseudoaneurysm complicating acute myocardial infarction: improved diagnosis by real time three dimensional echocardiography. Heart 2006. Feb, 92(2):154. IF: 7.369 Q1

Comunicacions i ponències

1. Fernandez-Rodriguez D, Regueiro A, Freixa X, Trilla M, Masotti M. Presence of "gender gap" inST-Segment Elevation Myocardial Infarction Networks. American Heart Association. 11/2015.

2. Freixa X, Llull L, Gafoor S, Cruz-Gonzalez I, Shakir S, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Kanagaratnam P, Nietlispach F, Gloekler S, Aminian A, Danna P,Rezzaghi M, Stock F, Stolcova M , Paiva L, Costa M, Millan X, Ibrahim R, Tichelbacker T, SchillingerW, Park JW, Sievert H, Meier B, Tzikas A. Clinical characterization of cerebrovascular events after left atrial appendage occlusion. APCASH. 10/2015.

3. Garcia E, Arzamendi D, Jimenez-Quevedo P, Sarnago F, Marti G, Sanchez-Recalde A, Larman M, Sancho M, Iniguez A, Goicolea J, Garcia San Roman K, Alonso Briales JH Molina E, Calabuig J, Freixa X, Berenguer A, Pinar E, Vazquez N, Diaz JF, Cruz-Gonzalez I. Spanish Real World Paravalvular Leaks Closure Registry (HOLE Registry). CSI. 06/2015

4. Freixa X, Gafoor S, Regueiro A, Cruz-Gonzalez I, Shakir S, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Sievert H, Tichelbacker T Kanagaratnam P, Nietlispach F, Aminian A, Danna P, Rezzaghi M, Stock F, Stolcova M , Paiva L, Costa M, Ibrahim R, , Schillinger W, Park JW, Meier B, Tzikas A. Safety and Efficacy of Left Atrial Appendage Occlusion in Elderly Patients. EuroPCR. 05/2015.

5. Martin-Yuste V, Hernandez M, Freixa X, Brugaletta S, Gomez-Monterrosas O, Scalone G, Sabate M. Gastrointestinal bleeding in patients with atrial fibrillation and anticoagulant therapy: the role of percutaneous atrial appendage closure. EuroPCR. 05/2015.

6. Otsuki S., Scalone G., Brugaletta S., Martin-Yuste V., Gomez O., Hernandez M., Romero S., Freixa X, Masotti M., Sabate M. Clinical outcome of acute recoil after everolimus-eluting bioresorbable vascular scaffolds implantation. EuroPCR. 05/2015.

7. Scalone G., Otsuki S., Brugaletta S., Martin Yuste V., Gomez O., Freixa X., Hernandez M., Romero S., Masotti M., Sabate M. In vivo comparison of acute recoil after everolimus-eluting bioresorbable vascular scaffolds implantation in thrombus containing vs. non-thrombus containing lesions. EuroPCR. 05/2015

8. M. Hernandez-Enriquez, O. Gomez-Monterrosas, X. Freixa, D. Pereda, D. Fernandez-Rodriguez, J.F. Encalada, S. Brugaletta, V. Martin-Yuste, M. Masotti, M. Sabate. Outcomes from surgical para-valvular leak repair versus percutaneous closure. ESC. 09/2015.

9. G. Scalone, S. Brugaletta, H.M. Garcia-Garcia, V. Martin-Yuste, Y. Azpeitia, S. Otsuki, O. Gomez, X. Freixa, M. Masotti, M. Sabate. Incidence and predictors of thrombus inside the guiding catheter. An optical coherence tomography study. ESC. 09/2015.

10. Regueiro A, Freixa X, Fernandez-Rodriguez D, Brugaletta S, Martin-Yuste V, Masotti M, Sabate M. Impact of therapeutic hypothermia on coronary flow. EuroPCR. 05/2014.

11. Tzikas A, Aguirre D, Velasco-Sanchez D, Freixa X, Alburquenque M, Khairy P, Bass JL, Ramirez J, Ibrahim R, Miro J. Transcatheter closure of perimembranous ventricular septal defect with the AmplatzerMembranous VSD Occluder 2. CSI. 06/2013.

12. Abualsaud A, Freixa X, Nosair M, Chan J, Tzikas A, Garceau P, Basmadjian A, Ibrahim R. Left atrial appendage occlusion with a second generation device. CCC. 10/2013.

13. Freixa X, Chan J, Tzikas A, Garceau P, Basmadjian A, Ibrahim R. Left atrial appendage occlusion with a second generation device. EuroPCR. 05/2013.

14. Freixa X, Ibrahim R, Chan J, Basmadjian A, Asgar A. The Gore Septal Occluder: Initial experience. CCC. 10/2012.

15. Freixa X, Almasood A, Asif N, Bui S, Ivanov J, Osten M, Ing D, Overgaard, Horlick E, Seidelin P, Dzavik V. Long-term outcomes using the crush and culotte techniques for the treatment of coronary bifurcations. TCT. 11/2011.

16. Freixa X, Carpen M, Kotowycz M, Ho KW, Krimly A, Osten M, Overgaard, M, Horlick E, Seidelin P, Davik V. Long-term outcomes after percutaneous intervention of the internal thoracic artery anastomosis: the use of drug-eluting stents is associated with a higher need of repeat revascularization. Canadian Congress of Cardiology. 10/2011.

17. Freixa X, Dzavik V, Forman S, Rankin J, Buller C, Cantor W, Ruzyllo W, Reynolds H, Lamas G, Hochman J. Long Term Outcomes Following a Strategy of PCI of the Infarct-related Artery with DES or BMS vs. Medical Therapy Alone In The Occluded Artery Trial (OAT). American Congress of Cardiology. New Orleans. 03/2011.

18. Khan S, Freixa X, Mackie K, Seidelin P, Dzavik V. Rotational Atherectomy via the Radial Artery Route is Safe With Equivalent Procedural Success Rates to the Traditional Femoral Route. American Heart Association Congress 2010. Chicago. 11/2010.

19. Freixa X, Almasood A, Wainstein R, Osherov A, Khan S, Horlick E, Seidelin P, Dzavik V. El uso del mismo tipo de stent para el tratamiento de las restenosis sobre stents recubiertos se asocia a una mayor tasa de revascularizacion. . Congreso de la Sociedad Espanola de Cardiologia 2010. Valencia. 10/2010.

20. Khan S, Freixa X, Mackie K, Seidelin P, Dzavik V. Rotational Atherectomy via the Radial Artery Route is Safe With Equivalent Procedural Success Rates to the Traditional Femoral Route. Canadian Cardiovascular Congress 2010. Montreal. 10/2010.

21. Freixa X, Almasood A, Wainstein R, Osherov A, Khan S, Horlick E, Seidelin P, Dzavik V. The use of a different drug eluting stent for the treatment of drug eluting stent restenosis is associated with a lower revascularization rate. Canadian Congress of Cardilogy 2010. Montreal. 10/2010.

22. Freixa X, Almasood A, Wainstein R, Osherov A, Horlick E, Seidelin P, Dzavik V. Placitaxel-eluting stent confer better long-term results for the treatment of drug-eluting stent fractures. Canadian Cardiovascular Congress. Montreal. 10/2010.

23. Freixa X, Almasood A, Wainstein R, Osherov A, Khan S, Horlick E, Seidelin P, Dzavik V. The use of a different drug eluting stent for the treatment of drug eluting stent restenosis is associated with a lower revascularization rate. TCT 2010. Washington. 09/2010.

24. Freixa X, Almasood A, Wainstein R, Osherov A, Horlick E, Seidelin P, Dzavik V. TaxusR stent confers better long-term results for the treatment of drug-eluting stent fractures. European Congress of Cardiology 2010. Stokholm. 09/2010.

25. Freixa X, Doltra A, Ortiz JT, Argiro S, Guasch E, Heras M, Jimenez M, Betriu A, Masotti M. Endothelin-1: A useful prognostic marker after acute myocardial infarction. American Heart Association 2009. Orlando. 11/2009.

26. Freixa X, Doltra A, Ortiz JT, Argiro S, Guasch E, Heras M, Jimenez M, Betriu A, Masotti M. Endothelin-1: A useful prognostic marker after acute myocardial infarction. European Congress of Cardiology 2009, Barcelona. 09/2009.

27. Masotti M, Freixa X, Bellera N, Jimenez M, Caralt, T, Ortiz JT, Pare C, Argiro S, Bosch X, Betriu A. Is postconditioning useless in acute myocardial infarction? European Congress of Cardiology. Barcelona. 09/2009.

28. Masotti M, Salazar H, Freixa X, Bellera N, Kiamco R, Fernandez C, Jimenez M, Argiro S, Betriu A. Role of embolic protection devices in acute myocardial infarction. Is their routine use of clinical Benefit at 6 months? World Congress of Cardiology. Buenos Aires 2008.

29. Masotti M, Freixa X, Bellera N, Kiamco R, Jimenez M, Argiro S, Fernandez C, Betriu A. Are women

at risk for poor outcomes after percutaneous coronary intervention for acute myocardial infarction? World Congress of Cardiology. Buenos Aires 2008.

30. Masotti M, Salazar H, Kiamco R, Freixa X, Betriu A. Embolic protection devices in acute myocardial infarction. Do they confer the same clinical benefit? American Heart Association. New Orleans. 03/2008.

31. Freixa X, Masotti M, Agiro S, Jimenez M, Pino M, Escolar G, Betriu A. Assessment of responsiveness to aspirin and clopidogrel by using a point of care platelet assay. European Congress of Cardiology 2008. Munich. 09/2008

32. Bellera N, Freixa X, Kiamco R, Fernandez-Gomez C, Argiro S, Jimenez M, iBetriu A, Masotti M. Effects of postconditioning on reperfusion and infarct size. European Congress of Cardiology 2008. Munich. 09/2008.

33. Masotti M, Salazar H, Kiamco R, Freixa X, Betriu A. Aspiration devices, but not thrombectomy or filters, improve prognosis following primary angioplasty. European Congress of Cardiology 2008. Munich. 09/2008.

34. Freixa X, Berruezo A, Magnani S, Mont Ll, Tolosana J.M, Benito B, Brugada J. Focal Atrial Tachycardia from the Right Atrial Appendage. Clinical and Electrocardiographic Characteristics. European Congress of Cardiology 2007. Viena. 09/2007

35. Freixa X, Berruezo A, Magnani S, Mont Ll, Tolosana J.M, Benito B, Brugada J. Focal Atrial Tachycardia from the Right Atrial Appendage. Clinical and Electrocardiographic Characteristics. Heart Rhythm 2007. Denver. 05/2007.

36. Freixa X, Berruezo A, Magnani S, Mont Ll, Tolosana J.M, Benito B, Brugada J. Focal Atrial Tachycardia from the Right Atrial Appendage. Clinical and Electrocardiographic Characteristics. Europace 2007. Lisboa. 06/2007.

37. Benito B, Tamborero D, Mont Ll, Berruelo A, Tarifa W, Freixa X, Brugada J. Basal plasmatic neurohormonal activation predicts the success of circumferential pulmonary veins ablation of atrial fibrillation. European Congress of Cardiology 2007. Viena. 09/2007.

38. Benito B, Mont L, Freixa X, Arzamendi D, Berruelo A, Tolosana JM, Brugada J. Outpatient vs Inpatient pacemaker implantation. Europace 2007. Lisboa. 06/2007.

39. Benito B, Mont L, Tamborero D, Berruelo A, Tarifa W, Freixa X. Basal plasmatic neurohormonal activation predicts the success of circumferential pulmonary veins ablation of atrial fibrillation. European Congress of Cardiology 2007. Viena. 09/2007.

40. Benito B, Mont L, Tamborero D, Berruelo A, Tarifa W, Freixa X. Basal plasmatic neurohormonal activation predicts the success of circumferential pulmonary veins ablation of atrial fibrillation.

Europace 2007. Lisboa. 06/2007.

41.Jiménez G, San Antonio R, Caixal G, Hernández-Enríquez M, Bosch X, Masotti M, Sabaté M, Freixa X. Hipotermia terapéutica y riesgo de thrombosis. Congreso de la Sociedad Espanola de Cardiologia 2015. Bilbao 10/2015.

42. M. Hernandez-Enriquez, O. Gomez-Monterrosas, X. Freixa, D. Pereda, D. Fernandez-Rodriguez, J.F. Encalada, S. Brugaletta, V. Martin-Yuste, M. Masotti, M. Sabate. Resultados del tratamiento quirurgico de fugas percutaneas comparado con el cierre percutaneo. Congreso de la Sociedad Espanola de Cardiologia. Bilbao 10/2015.

43. Hernandez-Enriquez M, Fernandez D, Regueiro-Cuevas A, Kasa G, Freixa X. Fuga peri-protesica aortica severa."Primer Concurso de Casos clinicos en Cardiopatia Estructural para Residentes de Cardiologia". Salamanca 02/2014.

44. Fernandez D, Barrufet M, Hernandez-Enriquez M, Riambau V, Freixa X. Cierre de endofuga de endoprotesis aortica mediante dispositivo para cierre de defecto interauricular: Nuevas utilidades para los dispositivos de cierre de defectos interauriculares. "Primer Concurso de Casos clinicos en Cardiopatia Estructural para Residentes de Cardiologia". Salamanca 02/2014.

45. Fernandez D, Vanini L, Hernandez-Enriquez M, Regueiro-Cuevas A, , Freixa X. Cierre de defectos interauriculares con multiples dispositivos en adultos. "Primer Concurso de Casos clinicos en Cardiopatia Estructural para Residentes de Cardiologia". Salamanca 02/2014.

46. Freixa X, Almasood A, Wainstein R, Osherov A, Khan S, Horlick E, Seidelin P, Dzavik V. El stent TaxusR proporciona mejores resultados para el tratamiento de las fracturas sobre stents recubiertos. Congreso de la Sociedad Espanola de Cardiologia 2010. Valencia 10/2010.

47. Jimenez M, Argiro S, Freixa X, Navarro JM, Feldman M, Maragano P, Betriu A, Masotti M. Cateterismo cardiaco por acceso transradial derecho e izquierdo en pacientes octogenarios. Congreso de la Sociedad Espanola de Cardiologia 2009. Barcelona. 10/2008.

48. Freixa X, Bellera N, Jimenez M, Caralt T, Ortiz JT, Argiro S, Betriu A, Masotti M. Es eficaz el postcondicionamiento durante el infarto agudo de miocardio? Congreso de la Sociedad Española de Cardiologia 2009. Barcelona. Oct 2009.

49. Freixa X, Sionis A, Castel A, Gusach E, Loma-Ososrio P, Arzamendi D, Roig E, Perez-Villa F. Low TroponinI levels on admission are associated with worse prognosis in patients with fulminant myocarditis. Congres de la Societat Catalana de Trasplantament. Barcelona 06/2009.

50. Freixa X, Masotti M, Argiro S, Jimenez M, Pino M, Escolar G, Pons F, Betriu A. Evaluacion de la concordancia entre sistemas de medida de agregacion plaquetaria en respuesta a aspirina y clopidogrel. Congreso de la Sociedad Espanola de Cardiologia. Bilbao 10/2008.

51. Masotti M, Bellera N, Freixa X, Kiamco C, Fernandez C, Argiro S, Jimenez M, Betriu A. Efecto de postcondicionamiento en la reperfusion y el tamano del infarto. Congreso de la Sociedad Espanola de Cardiologia. Bilbao 10/2008.

52. Masotti M, Salazar H, Freixa X, Kiamco R, Argiro S, Jimenez M, Betriu A. Los dispositivos de aspiracion, a diferencia de los filtros o trombectomia, mejoran el pronostico del infarto sometido a angioplastia primaria. Congreso de la Sociedad Espanola de Cardiologia. Bilbao 10/2008.

53. Freixa X, Masotti M, Heras M, Bellera N, Argiro X, Jimenez M, Betriu A. Relacion entre los niveles de Endotelina-1 y la funcion ventricular en el transcurso de un infarto agudo de miocardio. XX

Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2008.

54. Freixa X, Masotti M, Heras M, Bellera N, Argiro X, Jimenez M, Betriu A. Relacion entre los niveles de Endotelina-1 y la funcion ventricular en el transcurso de un infarto agudo de miocardio. XX Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2008.

55. Freixa X, Argiro S, Jimenez M, Pino M, Escolar G, Betriu A, Masotti M. Evaluacion de la concordancia entre los sistemas de medida de la agregacion plaquetaria en respuesta a la aspirina y clopidogrel. XX Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2008.

56. Freixa X, Masotti M, Kiamco R, Salazar H, Bellera N, Arzamendi D, Betriu A. Angioplastia Primaria en mujeres. Es el sexo un factor determinante en el pronostico? Congreso de la Sociedad Espanola de Cardiologia. Madrid. 10/2007.

57. Freixa X, Berruezo A, Magnani S, Mont Ll, Tolosana J.M, Benito B, Brugada J. Caracterizacion de las taquicardias auriculares de orejuela derecha. Congreso de la Sociedad Espanola de Cardiologia. Madrid. 10/2007.

58. Freixa X, Masotti M, Kiamco R, Salazar H, Bellera N, Arzamendi D, Betriu A. Angioplastia Primaria en dones. Es el sexe un factor determinant en el pronostic?. Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2007.

59. Freixa X, Perez-Villa F, L. Vidal, A. Carol, E. Roig. Els nivells baixos de Troponina I a l´ingres están relacionats amb un pitjor pronostic en els pacients amb miocarditis fulminant. XVIII Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2006.

60. Freixa X, Vidal B, Pare C, Barbera JA, Garcia-Aymerich J, Anto JM. Prevalenca de cardiopatia en pacients amb malaltia pulmonar obstructiva cronica de recent diagnostic. XVIII Congres de la Societat Catalana de Cardiologia. Barcelona. 06/2006.

61. Benito B, Tamborero D, Mont Ll, Berruelo A, Freixa X, Brugada J. El nivel de activación neurohormonal predice el exito de la ablacion circunferencial de venas pulmonares para el tratamiento de la fibrilacion auricular. Congreso de la Sociedad Espanola de Cardiologia. Madrid. 10/2007.

62. Garcia A, Arzamendi D, Loma-Osorio P, Freixa X, Bosch X, Betriu A. La revascularizacion precoz mejora la supervivencia de los pacientes con infarto agudo de miocardio complicado con shock cardiogenico. Congreso de la Sociedad Espanola de Cardiologia. Madrid. 10/2007.

63. Benito B, Mont L, Tamborero D, Berruelo A, Tarifa W, Freixa X. El nivel de activación neurohormonal predice el exito de la ablacion circunferencial de venas pulmonares para el tratamiento de la FA. VI Reunion Anual de la Seccion de Eectrofisiologia y Arritmias de la Sociedad Espanola de Cardiologia. Granada, 03/2007.

Reconeixements i certificats

Premi Extraordinari de Llicenciatura.

Beca Martin-Escudero de recerca a universitats o centres estrangers. 2012

Beca de la Societat Espanyola de Cardiologia per a la formació post-residència a centres estrangers 2010-2011

Beca de la Sociedad Española de Cardiología per a la formació post-residència a centres estrangers 2009-2010

Premi Emili Letang de final de residència de l'Hospital Clínic de Barcelona. Juny 2007

Beca de la Secció d’Hemodinàmica i de Cardiologia Intervencionista de la Sociedad Española de Cardiología. 2007

Primer premi per a la comunicació oral a la VI Reunió de la Secció d'Electrofisiologia i Arrítmies de la Sociedad Española de Cardiología. 2007

Segon premi al III Concurs de Casos Clínics per a residents en cardiologia. Segòvia d'Arana. 2005.

Finalista Nacional de les primeres beques Madaus per a Residents en Cardiologia. 2005